Development of nano-wiring methods using self-organization of DNAs

在这项研究中，我们试图通过DNA的自组织来建立利用金属纳米对象/DNA偶联物构建集成电路的技术。我们制备了二价DNA/金纳米颗粒(AuNP)偶联物，将两条DNA链连接在截然相反的位置。我们利用二价DNA/AuNP共轭化合物制备了具有可调节间距和几何构型的一维和二维AuNP阵列。为了获得高线性度的AuNP阵列，我们设计了并置的AuNP阵列系统，采用T基序和双交叉(DX)基序。利用T-基序和DX-基序可以更精确地排列和控制AuNPs之间的距离。此外，利用Holliday结形成共轭化合物，观察到了四方晶格状的2D结构。

In this study, we tried to establish the technique for construction of integrated circuit using metalic nano-object/DNA conjugates by self-organization of the DNAs. We prepared divalent DNA/gold nanoparticle(AuNP) conjugates attaching two DNA strands at diametrically opposed positions. We prepared one- and two-dimensional AuNP arrays with regulated distances and geometries using the divalent DNA/AuNP conjugates. To obtain AuNP arrays with high linearity, we designed AuNP array systems in juxtaposition using a T-motif and a double crossover (DX)-motif. More precise arrangements and control of distance between AuNPs can be achieved by using the T-motif and DX-motif. Moreover, tetragonal lattice-like 2D structure was observed by using Holliday junction forming conjugates.