Creation of new laminated polyvinyl alcohol hydrogel sheet aiming at application of artificial cartilage

制备了一种由3层含有不同浓度磷酸三钙的聚乙烯醇水凝胶（PVA-H）堆叠而成的新型层压凝胶片。每个薄片的厚度为1 mm，因此根据活的软骨，薄片的总厚度为3 mm。磷酸三钙填充PVA-H的拉伸和压缩性能均高于未填充PVA-H。另一方面，未填充的PVA-H显示出比填充的PVA-H更低的摩擦系数。结果发现，实现具有较低摩擦系数的高机械性能的有效手段是层压。使用激光轮廓仪测量水凝胶的磨损。将薄石墨膜粘附到凝胶片上以使凝胶表面与凝胶表面上的水膜隔离。结果表明，在磨料磨损条件下，磷酸三钙填料的作用不明显，而填充PVA-H的耐磨性与未填充PVA-H的相同。

A new laminated gel sheet piling up 3 lamellas of polyvinyl alcohol hydrogel (PVA-H) having different concentrations of tricalcium phosphate was created. Each lamella was 1mm in thickness, so that the total thickness of the sheet was 3 mm in accordance with vital cartilage. Both tensile and compressive properties of tricalcium phosphate-filled PVA-H were higher than those of unfilled PVA-H. On the other hand, unfilled PVA-H showed the lower coefficient of friction than the filled PVA-H. It was found that the effective means for achieving high mechanical properties with lower coefficient of friction was lamination. A laser profile meter was used to measure the wear of hydrogel. Thin graphite film was adhered onto the gel sheet to distinguishi the gel surface from the water film on the gel surface. As a result, the effect of tricalcium phosphate filler was not clear under abrasive wear condition, while the wear resistance of filled PVA-H was as the same as that of unfilled PVA-H.