Creation of new laminated polyvinyl alcohol hydrogel sheet aiming at application of artificial cartilage

用不同浓度的磷酸三钙将3片聚乙烯醇水凝胶(PVA-H)层叠在一起，制成了一种新型层状凝胶。每个板层的厚度为1 mm，因此该薄片的总厚度为3 mm，与重要的软骨相一致。填充磷酸三钙的PVA-H的拉伸和压缩性能均高于未填充的PVA-H。另一方面，未填充的PVA-H的摩擦系数低于填充的PVA-H。研究发现，层压是获得较高力学性能和较低摩擦系数的有效手段。用激光轮廓仪测量了水凝胶的磨损量。在凝胶片上附着一层薄薄的石墨膜，以区分凝胶表面和凝胶表面的水膜。结果表明，在磨粒磨损条件下，磷酸三钙的作用不明显，而填充的PVA-H的耐磨性与未填充的PVA-H相当。

A new laminated gel sheet piling up 3 lamellas of polyvinyl alcohol hydrogel (PVA-H) having different concentrations of tricalcium phosphate was created. Each lamella was 1mm in thickness, so that the total thickness of the sheet was 3 mm in accordance with vital cartilage. Both tensile and compressive properties of tricalcium phosphate-filled PVA-H were higher than those of unfilled PVA-H. On the other hand, unfilled PVA-H showed the lower coefficient of friction than the filled PVA-H. It was found that the effective means for achieving high mechanical properties with lower coefficient of friction was lamination. A laser profile meter was used to measure the wear of hydrogel. Thin graphite film was adhered onto the gel sheet to distinguishi the gel surface from the water film on the gel surface. As a result, the effect of tricalcium phosphate filler was not clear under abrasive wear condition, while the wear resistance of filled PVA-H was as the same as that of unfilled PVA-H.