Basic research to embolization uterie artery using NBCA Lipiodol in perinatal bleeding

NBCA碘油栓塞子宫动脉治疗围产期出血的基础研究

• 批准号: 23791444
• 负责人: HOSOKAWA takahiro
• 金额: $ 2.58万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23791444/
• 关键词: NBCA; 偽妊娠豚子宮動脈塞栓; 子宮動脈塞栓; 豚偽妊娠子宮動脈塞栓; 周産期出血

Perinatal bleeding is a condition that threatens the life of patient.Now, embolization from the uterine artery has been attempted. And embolization using NBCA has also increased.But there were a few pathological basic research after using NBCA.First, the uterine artery of two pigs was embolization using lipiodol and NBCA. Hysterectomy was performed to examine the extent of the NBCA and Lipiodol, and to observe in pathologic evaluation. The distribution of embolization material evaluated by soft X-ray was almost concordant by pathological evaluation. Second, after embolization using NBCA, two pigs were fed two weeks. Then angiography was performed to evaluate in the extent of embolic material. Then, we examined pathologically extent of embolic material, the effects on endometrium. In two weeks, it appeared that the degree of residual intravascular embolic material had different concentrations, but not change the extent of the range of distribution.

围产期出血是一种威胁患者生命的疾病，目前已尝试从子宫动脉进行栓塞。但应用NBCA后的病理学基础研究较少，首先，用碘油和NBCA栓塞了两头猪的子宫动脉。行子宫切除术，检查NBCA和碘油的范围，并进行病理学评价。软X线检查显示栓塞物分布与病理检查结果基本一致。第二，在使用NBCA栓塞后，喂养两头猪两周。然后进行血管造影以评估栓塞材料的范围。病理检查栓塞物的范围、对子宫内膜的影响。在两周内，血管内栓塞物质的残留程度有所不同，但分布范围的程度没有改变。

项目成果

豚偽妊娠子宮動脈に対するNBCAを用いた塞栓術後の塞栓範囲の検討、軟X線と病理組織標本の対比を中心に

重点检查猪假孕子宫动脉NBCA栓塞后的栓塞程度，并对比软X线片和病理组织标本。

• 发表时间: 2013
• 作者: Ikoma A;Kawai N;Sato M;Minamiguchi H;Nakata K;Nakai M;Sanda H;Sonomura T;Kanayama Y;Sakai Y;細川 崇洋
• 通讯作者: 細川 崇洋

豚偽妊娠子宮動脈に対するNBCAを用いた塞栓術後の塞栓範囲の検討,軟X線と病理組織標本の対比を中心に

猪假孕子宫动脉NBCA栓塞后的栓塞范围检查，重点是软X线与病理组织标本的比较

• 发表时间: 2013
• 作者: Ikoma A;Kawai N;Sato M;Minamiguchi H;Nakata K;Nakai M;Sanda H;Sonomura T;Kanayama Y;Sakai Y;細川 崇洋;細川崇洋
• 通讯作者: 細川崇洋