A research on the optimal protocol for cryoablation of endocrine organ including adrenal gland and thyroid gland

肾上腺、甲状腺等内分泌器官冷冻消融最佳方案的研究

• 批准号: 23791448
• 负责人: SOTA Oguro
• 金额: $ 2.58万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23791448/
• 关键词: 凍結療法; 副腎; 甲状腺; 副腎の凍結療法; 甲状腺の凍結療法

Cryoablation of the adrenal gland caused a hypertensive crisis during thawing. This hypertensive crisis was conducted by high plasma catecholamines and was observed rapidly. We concluded that the blood pressure should be monitored and controlled using arterial blood pressure and arterial infusion of alpha-blocker.Cryoablation of the thyroid gland revealed that the area of the ice ball was significantly smaller than that of liver or kidney. The size of the ice ball was different in each experiments. This difference in the size of the ice ball was caused by "heat sink effect" by a regional vessels including common carotid artery or vein.

肾上腺冷冻消融在解冻过程中引起高血压危象。这种高血压危象是由高血浆儿茶酚胺引起的，并且被迅速观察到。我们的结论是，应通过动脉血压和动脉输注α受体阻滞剂来监测和控制血压。甲状腺冷冻消融显示冰球的面积明显小于肝脏或肾脏的面积。每个实验中冰球的大小都不同。冰球大小的差异是由包括颈总动脉或静脉在内的局部血管的“散热效应”引起的。

项目成果

甲状腺の凍結療法時におけるホルモンおよびバイタルの変化について

甲状腺冷冻治疗期间的荷尔蒙和生命变化

• 作者: 小黒 草太;中塚 誠之;井上 政則;橋本 統;栗林 幸夫
• 通讯作者: 栗林 幸夫

Hemodynamic and hormonal changes during cryoablation of adrenal gland in swine : in vivo experimental study

猪肾上腺冷冻消融过程中血流动力学和激素的变化：体内实验研究

• 发表时间: 2011
• 作者: M. Inoue;S. Nakatsuka;H. Yashiro;S. Oguro;N. Ito;Y. Yamauchi;K. Hashimoto;K. Asakura;N. Tsukada;Y. Izumi;M. Kawamura;S. Kuribayashi
• 通讯作者: S. Kuribayashi

Hemodynamic and hormonal changes during cryoablation of adrenal gland in swine: in vivo experimental study

猪肾上腺冷冻消融过程中血流动力学和激素的变化：体内实验研究

• 发表时间: 2011
• 作者: M. Inoue;S. Nakatsuka;H. Yashiro;S. Oguro;N. Ito;Y. Yamauchi;K. Hashimoto;K. Asakura;N. Tsukada;Y. Izumi;M. Kawamura;S. Kuribayashi
• 通讯作者: S. Kuribayashi

ブタ甲状腺の凍結療法時におけるホルモンおよびバイタルの変化について

猪甲状腺冷冻治疗期间的激素和生命变化

• 发表时间: 2012
• 作者: 小黒草太;中塚誠之;井上政則;橋本統;栗林幸夫
• 通讯作者: 栗林幸夫

Transcatheter Arterial Chemoembolization (TACE) of Liver Metastases From Malignant Pheochromocytoma of the Adrenal Gland

肾上腺恶性嗜铬细胞瘤肝转移的经导管动脉化疗栓塞 (TACE)

• 发表时间: 2012
• 作者: S. Oguro;S. Hashimoto;Y. Matsusaka;M. Inoue;S. Nakatsuka;S. Kuribayashi
• 通讯作者: S. Kuribayashi