A research on the optimal protocol for cryoablation of endocrine organ including adrenal gland and thyroid gland

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Cryoablation of the adrenal gland caused a hypertensive crisis during thawing. This hypertensive crisis was conducted by high plasma catecholamines and was observed rapidly. We concluded that the blood pressure should be monitored and controlled using arterial blood pressure and arterial infusion of alpha-blocker.Cryoablation of the thyroid gland revealed that the area of the ice ball was significantly smaller than that of liver or kidney. The size of the ice ball was different in each experiments. This difference in the size of the ice ball was caused by "heat sink effect" by a regional vessels including common carotid artery or vein.