Mechanism of cell wall thickening in drug-resistant bacteria

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Conventionally, had been reported that there is no difference in the morphological sensitive bacteria and drug-resistant bacteria. However, it has a feature that cell wall thickening as ultrastructural features VISA (Vancomycin-Resistant Staphylococcus aureus) in 1997 since, it has attracted attention for the bacterial cell wall. We have reported that examined the ultrastructural characteristics for ML -resistant staphylococci isolated from chronic sinusitis patients have morphological characteristics of cell wall thickening. We were examined whether having the morphological characteristics in drug-resistant bacteria in general in this study. In the case of ML -resistant bacteria , has a characteristic of cell wall thickening , but also for multi-drug resistant S. aureus against S. aureus similar results were obtained , cell wall thickening of multiple-drug-resistant bacteria has been pointed out may contribute the protein synthesis inhibitor .