The Regeneration of cementum by Using Cementoblast

目前，修复体治疗如冠桥、可摘义齿和牙种植体是常用的。另一方面，与天然牙齿相比，人工材料储存的创伤或先天性/后天性牙齿缺损在生物相容性、美学、功能性方面存在各种问题。这项研究描绘了如何再生治疗应用于临床牙科。本文首先对应用组织工程技术的牙再生，特别是牙骨质再生和牙修复材料进行了研究。近年来，研究发现牙骨质再生不仅需要较长的时间才能完成组织再生，而且再生组织过早且体积小。本研究探讨体外培养的牙源性细胞分层对细胞生长、分化和组织再生能力的影响。然后，对细胞培养和组织再生方法进行定量和定性的验证。

At present prosthesis treatments such as crown/bridge, removable denture and dentalimplant are commonly performed. On the other hand, trauma or congenital/aquiried tooth defect is stored by artificial materials have various issues in terms of biocompability, esthetics, functoionality, compared to natural teeth. This study delineates how regenerative therapy is applied to clinical dentistry. As a first step, we examined tooth regeneration which applied tissue engineering technique, especially cementum regeneration and tooth prosthesis materials. Recently, it is found that not only does cementum regenetration take a long period to complete tissue regeneration but also turnregenerated tissue premature and small. This research examines how cultured odontogenic cell stratification will affect the ability of cell growth and differentiation and tissue regeneration. Then, it intends to prove cell culture and tissue regeneration method quantitavely and qualitively.