The Regeneration of cementum by Using Cementoblast

目前常用的修复方法有冠/桥、可摘义齿、义齿等。另一方面，创伤或先天性/获得性牙齿缺陷是由人工材料保存的，与天然牙齿相比，人工材料在生物相容性、美观性、功能性等方面存在各种问题。这项研究描述了再生疗法如何应用于临床牙科。作为第一步，我们研究了应用组织工程技术的牙齿再生，特别是牙骨质再生和牙齿修复材料。最近发现，牙骨质再生不仅需要较长的时间才能完成组织再生，而且会使再生组织过早而细小。这项研究考察了培养的牙源性细胞分层如何影响细胞的生长和分化以及组织再生的能力。在此基础上，对细胞培养和组织再生方法进行了定性和定量的论证。

At present prosthesis treatments such as crown/bridge, removable denture and dentalimplant are commonly performed. On the other hand, trauma or congenital/aquiried tooth defect is stored by artificial materials have various issues in terms of biocompability, esthetics, functoionality, compared to natural teeth. This study delineates how regenerative therapy is applied to clinical dentistry. As a first step, we examined tooth regeneration which applied tissue engineering technique, especially cementum regeneration and tooth prosthesis materials. Recently, it is found that not only does cementum regenetration take a long period to complete tissue regeneration but also turnregenerated tissue premature and small. This research examines how cultured odontogenic cell stratification will affect the ability of cell growth and differentiation and tissue regeneration. Then, it intends to prove cell culture and tissue regeneration method quantitavely and qualitively.