The effects of the degradation of mucin by Streptococci on the mechanism of oral malodor

链球菌降解粘蛋白对口腔恶臭机制的影响

• 批准号: 23792532
• 负责人: TANIGUCHI NAO
• 金额: $ 2.58万
• 依托单位: Fukuoka Dental College
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23792532/
• 关键词: 揮発性硫黄化合物; 口腔内細菌叢; 口臭; 高速シーケンス解析; グルコシダーゼ; 唾液; β-galactosidase; βガラクトシダーゼ; 舌苔; 口腔内細菌; galactosidase; volatile sulfur compound; halitosis; oral streptococci; physiologic halitosis

Salivary beta-galactosidase activity from the patients complaining of halitosis was measured and compared between the periodontally healthy group and the periodontitis group. Positive correlations were observed between the beta-galactosidase activity and oral malodor levels in the periodontally healthy group. Concerning the clinical parameter, the plaque index and tongue coating score were positively correlated with beta-galactosidase activity in the periodontal healthy group. Next, the bacterial compositions of saliva exhibiting higher and lower malodor were explored in order to determine the specific microbial community related to oral malodor. In addition, the compositions of oral microbiota associated with high hydrogen sulfide and methyl mercaptan production were determined. Tongue coating is main sources of oral malodor, and therefore the beta-galactosidase activity of tongue coating was measured.

对牙周健康组和牙周炎组的口臭患者唾液β-半乳糖苷酶活性进行检测和比较。牙周健康组的β-半乳糖苷酶活性与口腔异味水平呈正相关。牙周健康组的菌斑指数、舌苔评分与β-半乳糖苷酶活性呈正相关。接下来，研究了表现出较高和较低恶臭的唾液的细菌组成，以确定与口腔恶臭相关的特定微生物群落。此外，还测定了与高硫化氢和甲基苯丙胺产生相关的口腔微生物群的组成。舌苔是口腔恶臭的主要来源，因此测定舌苔中β-半乳糖苷酶的活性。

项目成果

Oral Health Care - Prosthodontics, Periodontology, Biology, Research and Systemic Conditions

口腔保健 - 口腔修复学、牙周病学、生物学、研究和系统性疾病

• DOI: 10.5772/2520
• 发表时间: 2012
• 作者: M. Virdi

ザクインテッセンス

精髓

• 发表时间: 2016
• 作者: 西条美紀;渡辺聡;興地隆史
• 通讯作者: 興地隆史

Relationship between oral malodor and oral microbiota. Oral Health Care-rosthodontics, Periodontology, Biology, Research and Systemic Conditions

口腔恶臭与口腔微生物群的关系。

• 发表时间: 2012
• 作者: Suzuki N;Yoneda M;Hirofuji T
• 通讯作者: Hirofuji T

Awareness among dental hygienists with regard to treatment options for halitosis.

牙科保健员对口臭治疗方案的认识。

• 发表时间: 2012
• 期刊: International Journal of Clinical Preventive Dentistry
• 作者: Yoneda M;Kashio N;Uchida H;Suzuki N;Matsuura H;Naito T;Koga C;Yasukochi H;Matsuura M;Hirofuji T.
• 通讯作者: Hirofuji T.

S-PRGイオン溶出液とS-PRG配合歯面研磨剤の口腔バイオフィルムへの影響

S-PRG离子洗出液和S-PRG混合牙面抛光剂对口腔生物膜的影响

• 发表时间: 2012
• 作者: 桝尾陽介;鈴木奈央;米田雅裕;安忠大;仲西宏介;藤本暁江;伊波幸作;瀬野恵衣;山田和彦;岩元知之;廣藤卓雄
• 通讯作者: 廣藤卓雄