Investigation on neural mechanisms of the effect of touch using an indicator of cardiovascular responses to painful stimuli
Investigation on neural mechanisms of the effect of touch using an indicator of cardiovascular responses to painful stimuli
批准号:
23792575
负责人:
WATANABE Nobuhiro
金额:
$2.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
The present study examined the effect of gentle cutaneous stimulation (touch) and its mechanism using heart rate responses to noxious heat stimulation as an indicator in anesthetized rats. We found that touch using a soft elastomer brush inhibited heat-induced heart rate responses. Additionally, the inhibitory effect of touch on heart rate responses was abolished by blocking spinal μ-opioid receptors.
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