Development of surgery probe of deep brain stimulation integrated with CMOS microchips

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A novel clinical medical tool for surgical operation of deep brain stimulation was fabricated and evaluated. Dedicated micro-CMOS image sensor was mounted on the tip of quite fine probe tube. The probe has the same diameter as a probe that is utilized in surgical operation. In this study, stimulation and recording function of nerve were also integrated into the CMOS microchip. The CMOS microchips were assembled onto a flexible substrate with stimulus/recording electrodes. A prototype of proposed device was developed successfully, and functional evaluation was performed.