To reveal a cause of development of hypertension with long term measurement of sympathetic nerve activity

高血压是一种疾病。世界上四分之一的成年人被诊断患有高血压。本研究的目的是探讨交感神经活动在高血压初期发展中的潜在作用。本研究的目的是探讨交感神经活动在高血压初期发展中的潜在作用。本实验采用盐敏感、超敏感大鼠和卒中易感自发性高血压大鼠。长期用双极电极测量大鼠肾（RSNA）和腰交感神经活动（LSNA），用遥测仪测量动脉压（AP）和心率（HR）。RSNA和LSNA在高血压发生时没有明显升高。因此，交感神经活动对这些过敏大鼠高血压的初始发展的可能贡献仍不确定。

Hypertension is a disease. One in four adults in the world have been diagnosed with high blood pressure. The aim of the present study was to explore a potential role of sympathetic nerve activity in the initial development of hypertension. The aim of the present study was to explore a potential role of sympathetic nerve activity in the initial development of hypertension. Salt sensitive hypersensitive rats and stroke-prone spontaneously hypertensive rats were used this experiments. The rats were chronically instrumented with a bipolar electrode for measurements of renal (RSNA) and lumbar sympathetic nerve activity (LSNA) and telemeter for measurements of arterial pressure (AP) and heart rate (HR). RSNA and LSNA apparently did not increase while development of hypertension occurred. It is therefor likely that possible contribution of sympathetic nerve activity to the initial development of hypertension in those hypersensitive rats remains uncertain.