ATP/adenosine as a critical link between altered metabolism and neuronal activity
ATP/adenosine as a critical link between altered metabolism and neuronal activity
批准号:
23790303
负责人:
KAWAMURA Masahito
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The “cause-and-effect” relationship between altered metabolism and the neurological conditions are not fully understood yet. We hypothesized that ATP/adenosine might play a specific role in modulating neuronal activity to produce the anticonvulsant effects of the ketogenic diet. We found that ketogenic diet-induced antiseizure effect is caused by ATP release with the subsequent activation of adenosine A_1 receptors.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
アデノシン受容体の活性化を介した海馬アストロサイト自発的カルシウム・オシレーション頻度の長期増強
通过激活腺苷受体长期增强海马星形胶质细胞自发钙振荡频率
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[N.Ikarashi, R.Kon, T.Iizasa, N.Suzuki, R.Hiruma, K.Suenaga, T.Toda, M.Ishii, M.Hoshino, W., 今西正樹, 川村将仁]
通讯作者:
川村将仁
DOI:
10.1016/j.physbeh.2011.04.001
发表时间:
2011-07-06
期刊:
PHYSIOLOGY & BEHAVIOR
影响因子:
2.9
作者:
[Ruskin, David N., Ross, Jessica L., Kawamura, Masahito, Jr., Ruiz, Tiffany L., Geiger, Jonathan D., Masino, Susan A.]
通讯作者:
Masino, Susan A.
Metabolism and Purinergic Autocrine Regulation. (ワークショップ)
代谢和嘌呤能自分泌调节(研讨会)
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Kawamura M, Jr.]
通讯作者:
Jr.
Adenosine and autocrine metabolic regulation of neuronal activity. In:Adenosine: a Key Link between Metabolism and CNS Activity (Masino SA, Boison D, eds)
腺苷和神经元活动的自分泌代谢调节。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Kawamura M, Jr., Ruskin DN]
通讯作者:
Ruskin DN
Adenosine-mediated inhibition of excitatory transmission during ischemia at different temperatures in the hippocampus.
不同温度下海马缺血期间腺苷介导的兴奋性传递抑制。
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[M. Kutsukake, M. Kobayashi, K. Tamura, M.Yoshie, E. Tachikawa, A. Matsuda, E. Uchida,and T. Matsutani, Kawamura M]
通讯作者:
Kawamura M
共 15 条
The involvement of ATP/adenosine in the therapeutic hypothermia for brain ischemia
-
批准号:25860193
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.75万
-
财政年份:2013
-
负责人:KAWAMURA Masahito
-
依托单位:
海外基金