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ATP/adenosine as a critical link between altered metabolism and neuronal activity

ATP/adenosine as a critical link between altered metabolism and neuronal activity
ATP/腺苷是代谢改变和神经元活动之间的关键联系
批准号:
23790303
负责人:
KAWAMURA Masahito
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
The “cause-and-effect” relationship between altered metabolism and the neurological conditions are not fully understood yet. We hypothesized that ATP/adenosine might play a specific role in modulating neuronal activity to produce the anticonvulsant effects of the ketogenic diet. We found that ketogenic diet-induced antiseizure effect is caused by ATP release with the subsequent activation of adenosine A_1 receptors.
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DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [N.Ikarashi, R.Kon, T.Iizasa, N.Suzuki, R.Hiruma, K.Suenaga, T.Toda, M.Ishii, M.Hoshino, W., 今西正樹, 川村将仁]
通讯作者: 川村将仁
DOI: 10.1016/j.physbeh.2011.04.001
发表时间: 2011-07-06
期刊: PHYSIOLOGY & BEHAVIOR
影响因子: 2.9
作者: [Ruskin, David N., Ross, Jessica L., Kawamura, Masahito, Jr., Ruiz, Tiffany L., Geiger, Jonathan D., Masino, Susan A.]
通讯作者: Masino, Susan A.
Metabolism and Purinergic Autocrine Regulation. (ワークショップ)
代谢和嘌呤能自分泌调节(研讨会)
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Kawamura M, Jr.]
通讯作者: Jr.
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Kawamura M, Jr., Ruskin DN]
通讯作者: Ruskin DN
15
    The involvement of ATP/adenosine in the therapeutic hypothermia for brain ischemia
    • 批准号:
      25860193
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.75万
    • 财政年份:
      2013
    • 负责人:
      KAWAMURA Masahito
    • 依托单位:
    海外基金