A study on the association between urinary aluminum concentration and pre-clinical findings among aluminum handling and non-handling workers

为了估计铝对人体的毒性，我们测量了铝搬运工人和非铝搬运工人尿液中的铝浓度，并探讨了尿铝浓度与临床前研究结果的关系。铝搬运工人尿液中铝浓度为5.4 ~ 55.1ug/g cre，非搬运工人尿液中铝浓度为5.6 ~ 15.6ug/g cre。它们之间有显著的差异。临床前研究结果无显著差异。虽然铝搬运工人的尿中铝排泄量增加，但至少在尿中铝低于55ug/g cre的情况下，铝对人体无害。

In order to estimate the toxicity of aluminum to humans, we measure the aluminum concentration in urine among the aluminum handling and non-handling workers and investigate the relationships between the urinary aluminum concentration and the pre-clinical findings. The aluminum concentration in urine ranges from 5.4-55.1ug/g cre in the aluminum handling workers and the aluminum concentration in urine ranges from 5.6-15.6ug/g cre in the non-handling workers. There are significant differences between them. There are no significant differences in the pre-clinical findings. Although the excretion of aluminum in urine increases in aluminun handling workers, it is demonstrated that aluminum is not harmful to humans, at least in case that aluminum in urine is below 55ug/g cre.