Basic research for the oscillations of the brain metabolism in neonates: analysis of the relationship between NIRS and EEG.

低频振荡(LFO)被定义为0.01-0.1赫兹之间的频率，在监测脑血流、代谢和功能方面越来越受到重视。之前的报告调查了早产儿的NIRS和EEG，发现在痕迹交替的EEG阶段，LFO和猝发活动之间存在明显的一致性。他们得出结论，NIRS-LFOS可能是爆发活动中耗氧量引起的BOLD现象的结果。本研究旨在探讨健康新生儿各睡眠阶段大脑皮层活动与NIRS-LFOS的关系。我们测量了13条记录。结果如下：证实了大脑皮层电活动与NIRS-LFOS的相关性，NIRS-LFOS的功率在睡眠的各个阶段都有观察到。由于NIRS-LFOS的发生没有大脑皮层的活动，这表明大脑皮层活动的起源和LFO在氧气可利用性中的存在。

Low frequency oscillations (LFOs), which are defined as frequencies between 0.01-0.1 Hz, have increasingly recognized using monitoring cerebral blood flow, metabolism and function. Previous report ,which investigated NIRS and EEG in preterm infants, found pronouncing coherence between LFOs and burst activities during the trace alternant EEG phase. They concluded that NIRS-LFOs might be the consequence of BOLD phenomenon induced by oxygen consumption during burst activities. The aim of this study was to investigate the relationship between electro-cortical activities and NIRS-LFOs during every sleep stages in healthy neonates. We measured 13 records. The results were as below, we confirmed the correlation between electro-cortical activities and NIRS-LFOs, the power of NIRS-LFOs was observed every sleep stages. Because NIRS-LFOs occurred without electro-cortical activities, it suggested the existence of the origin of electro-cortical activities and LFOs in oxygen availability.