课题基金 / 基金详情

Investigation of diagnostic and prognostic markers of severe cutaneous adverse drug reactions

Investigation of diagnostic and prognostic markers of severe cutaneous adverse drug reactions
严重皮肤药物不良反应诊断和预后标志物的研究
批准号：
23791243
负责人：
MURATA Jyunko
金额：
$2.66万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2011
资助国家：
日本
项目状态：
已结题
起止时间：
2011 至 2012
来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23791243/
关键词：
皮膚炎症再生学重症薬疹中毒性表皮壊死症Stevens-Johnson症候群早期診断マーカー可溶性FasLグラニュライシン薬剤過敏症症候群

项目摘要

项目成果

MURATA Jyunko的其他基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Severe cutaneous adverse drug reactions (Stevens-Johnson syndrome and toxic epidermal necrolysis) are life-threating diseases.In this project, we investigated to identify diagnostic and prognostic markers using patients’ PBMCs. Patients’ PBMCs were stimulated with causative drugs and mRNA and proteins were collected. These mRNA and proteins profiles were compared to those of non-severe cutaneous adverse drug reactions (maculopapular tyoe).We identified sFasL and granulysin are the markers.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Development of diagnostic test for cutaneous adverse drug reaction.
  • 批准号：
    25860924
  • 项目类别：
    Grant-in-Aid for Young Scientists (B)
  • 资助金额：
    $2.66万
  • 财政年份：
    2013
  • 负责人：
    MURATA Jyunko
  • 依托单位：
    Hokkaido University