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Establishment in evaluating antitumor immunity of inactivated HVJ-Eto malignant melanoma

Establishment in evaluating antitumor immunity of inactivated HVJ-Eto malignant melanoma
灭活HVJ-Eto恶性黑色素瘤抗肿瘤免疫评价的建立
批准号:
23791268
负责人:
TANEMURA Atsushi
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
We evaluated the inducible humoral and cellular immunity of inactivated HVJ-E in the patients with advanced malignant melanoma. As results, we detected a novel and specific auto-antibody which was upregulated with HVJ-E administration in human as well as in melanoma cells bearing mice. CD4^+/ CD8^+T cells and CD11c^+dendritic cells robustly infiltrated particularly into the shrinking melanoma tissues, indicating that HVJ-E could augment the comprehensive anti-tumor immunity in malignant melanoma.
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DOI: --
发表时间: 2013
期刊: Cancer Gene Therapy
影响因子: 6.4
作者: [Shigeru Matsumura, Mayumi Hamasaki, Takuya Yamamoto, Miki Ebisuya, Mizuho Sato, Eisuke Nishida, Fumiko Toyoshima, Atsushi Tanemura]
通讯作者: Atsushi Tanemura
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Hayashi M, Suzuki T, Atsushi Tanemura]
通讯作者: Atsushi Tanemura
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