Establishment in evaluating antitumor immunity of inactivated HVJ-Eto malignant melanoma
Establishment in evaluating antitumor immunity of inactivated HVJ-Eto malignant melanoma
批准号:
23791268
负责人:
TANEMURA Atsushi
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
We evaluated the inducible humoral and cellular immunity of inactivated HVJ-E in the patients with advanced malignant melanoma. As results, we detected a novel and specific auto-antibody which was upregulated with HVJ-E administration in human as well as in melanoma cells bearing mice. CD4^+/ CD8^+T cells and CD11c^+dendritic cells robustly infiltrated particularly into the shrinking melanoma tissues, indicating that HVJ-E could augment the comprehensive anti-tumor immunity in malignant melanoma.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Recent Advance and Development in Antitumor Effect of HVJ Envelope Vector in Malignant Melanoma; from Bench to Clinical Application
HVJ包膜载体抗恶性黑色素瘤作用的最新进展
DOI:
--
发表时间:
2013
期刊:
Cancer Gene Therapy
影响因子:
6.4
作者:
[Shigeru Matsumura, Mayumi Hamasaki, Takuya Yamamoto, Miki Ebisuya, Mizuho Sato, Eisuke Nishida, Fumiko Toyoshima, Atsushi Tanemura]
通讯作者:
Atsushi Tanemura
A Clinical Study Using the Hemagglutinating Virus of Japan-Envelope on Patients with Progressive Malignant Melanoma
日本信封血凝病毒治疗进展性恶性黑色素瘤的临床研究
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Hayashi M, Suzuki T, Atsushi Tanemura]
通讯作者:
Atsushi Tanemura
海外基金