Development of Light-induced Membrane Proteins as a High-sensitiveMembrane Potential Sensor
Development of Light-induced Membrane Proteins as a High-sensitiveMembrane Potential Sensor
批准号:
23657096
负责人:
DEMURA Makoto
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012 至 2013
中文摘要
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英文摘要
Human eye has a light-sensitive membrane protein. This sensor protein called rhodopsin that can identify the color of the light. Contrary, a rhodopsin-like proteins were found in some microorganisms, which have a light-driven ion transport (membrane potential) features different from the eyes. In this study, in order to improve the light-driven ion transport of microbial rhodopsin, the modified rhodopsins were prepared and visible absorption spectra in equilibrium and transient states, and the trimeric structure of modified rhodopsins were investigated.
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Overexpression and Analysis of precursor Human Defensin5
前体人类防御素 5 的过表达和分析
DOI:
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发表时间:
2011
期刊:
影响因子:
--
作者:
[Yumi Ogata, Tomoyasu Aizawa, Naoki Sakai, Masakatsu Kamiya, Takashi Kikukawa, Yasuhiro Kumaki, Makoto Demura, Tokiyoshi Ayabe, Keiichi Kawano]
通讯作者:
Keiichi Kawano
ダイナミクスインフォマ ティクス「光で動くタンパク質・イオンポンプ」
动力学信息学“光动力蛋白质/离子泵”
DOI:
--
发表时间:
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影响因子:
--
作者:
[]
通讯作者:
Homo-trimeric structure of Gloeobacter rhodopsin is regulated by the protonation state of Asp121, a counterion of the protonated Schiff base
胶杆菌视紫红质的同源三聚结构受 Asp121(质子化希夫碱的抗衡离子)的质子化状态调节
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Tsukamoto, T., Kikukawa, T., Kurata, T., Jung, K-H., Kamo, N., Demura, M.]
通讯作者:
M.
三次元固体NMR 法による膜タンパク質ハロロドプシンの研究
三维固态核磁共振法研究膜蛋白卤视紫红质
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[田巻初, 江川文子, 神谷昌克, 菊川峰志, 相沢智康, 河野敬一, 藤原敏道, 出村誠]
通讯作者:
出村誠
Decay kinetics of the M photointermediate of bacteriorhodopsin in short chain phosphatidylcholine micelles
短链磷脂酰胆碱胶束中细菌视紫红质 M 光中间体的衰变动力学
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Hasebe, A., Mayahara, M., Narita, K., Oda, M., Nakamura, M., Kuroda, S. and Niimi, T., 尾山 大明, 桑原由美子,福元美奈,菊川峰志,出村誠,園山正史]
通讯作者:
桑原由美子,福元美奈,菊川峰志,出村誠,園山正史
共 63 条
Development and structural characteristic of apoptosis-inducing α-lactalbumin
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批准号:16570129
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2004
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负责人:DEMURA Makoto
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依托单位:
海外基金