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Is insulin inactivated by the binding with serum soluble insulin receptor(sIR)?

Is insulin inactivated by the binding with serum soluble insulin receptor(sIR)?
胰岛素是否会因与血清可溶性胰岛素受体(sIR)结合而失活?
批准号:
23659156
负责人:
EBINA Yousuke
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
W e have established ultrasensitive ELISA insulin assay system.With the anti-IR antibody which does not inhibit the binding of sIR with insulin,we could measure the insulin which binds to sIR.We have succeeded to precipitate sIR-insulin complex by the monoclonal antibody 18-44 without affecting sIR-insulin complex.
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Molecular mechanisms of Insulin signal transduction and diabetes mellitus
  • 批准号:
    20390095
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $12.56万
  • 财政年份:
    2008
  • 负责人:
    EBINA Yousuke
  • 依托单位:
Molecular mechanisms of insulin signal transduction and diabetes mellitus
  • 批准号:
    18390104
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $10.77万
  • 财政年份:
    2006
  • 负责人:
    EBINA Yousuke
  • 依托单位:
Molecular mechanisms of insulin signal transduction and diabetes mellitus
  • 批准号:
    16390097
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $9.54万
  • 财政年份:
    2004
  • 负责人:
    EBINA Yousuke
  • 依托单位:
Molecular mechanisms of insulin signal transduction and diabetes mellitus
  • 批准号:
    14370045
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $8.9万
  • 财政年份:
    2002
  • 负责人:
    EBINA Yousuke
  • 依托单位:
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