Is insulin inactivated by the binding with serum soluble insulin receptor(sIR)?
Is insulin inactivated by the binding with serum soluble insulin receptor(sIR)?
批准号:
23659156
负责人:
EBINA Yousuke
金额:
$2.41万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
W e have established ultrasensitive ELISA insulin assay system.With the anti-IR antibody which does not inhibit the binding of sIR with insulin,we could measure the insulin which binds to sIR.We have succeeded to precipitate sIR-insulin complex by the monoclonal antibody 18-44 without affecting sIR-insulin complex.
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会议论文
Molecular mechanisms of Insulin signal transduction and diabetes mellitus
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批准号:20390095
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.56万
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财政年份:2008
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负责人:EBINA Yousuke
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依托单位:
Molecular mechanisms of insulin signal transduction and diabetes mellitus
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批准号:18390104
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.77万
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财政年份:2006
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负责人:EBINA Yousuke
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依托单位:
Molecular mechanisms of insulin signal transduction and diabetes mellitus
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批准号:16390097
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.54万
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财政年份:2004
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负责人:EBINA Yousuke
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依托单位:
Molecular mechanisms of insulin signal transduction and diabetes mellitus
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批准号:14370045
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.9万
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财政年份:2002
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负责人:EBINA Yousuke
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依托单位:
Development of a drug for diabetes using human genome information
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批准号:13557011
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.9万
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财政年份:2001
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负责人:EBINA Yousuke
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依托单位:
Molecular mechanisms of insulin signal transduction and diabetas mellitus
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批准号:12470027
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.15万
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财政年份:2000
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负责人:EBINA Yousuke
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依托单位:
Molecular mechanisms of insulin signal transduction and diabetes mellitus
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批准号:10470032
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.19万
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财政年份:1998
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负责人:EBINA Yousuke
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依托单位:
Development of a simple screening system for the discovery of a new drug for diabetes
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批准号:10557019
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$8.38万
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财政年份:1998
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负责人:EBINA Yousuke
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依托单位:
Development of a simple screening system for the discovery of a new drug for diabetes
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批准号:08558074
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$8.83万
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财政年份:1996
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负责人:EBINA Yousuke
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依托单位:
Molecular mechanisms of insulin signal transduction and diabetes mellitus
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批准号:08457050
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.99万
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财政年份:1996
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负责人:EBINA Yousuke
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依托单位:
Molecular mechanisms of insulin signal transduction and diabetes mellitus
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批准号:06454178
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.67万
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财政年份:1994
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负责人:EBINA Yousuke
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依托单位:
Molecular mechanisms of insulin signal transduction and its disorder
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批准号:03454161
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.16万
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财政年份:1991
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负责人:EBINA Yousuke
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依托单位:
Establishment of a simple diagnostic method for the detection of mutations of insulin receptor gene in Non-Insulin Dependent Diabetes Mellitus
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批准号:02557017
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$9.86万
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财政年份:1990
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负责人:EBINA Yousuke
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依托单位:
Structure and Function of Insulin Receptor, its Gene Expression and its Signal Transduction Mechanism
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批准号:01480148
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.35万
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财政年份:1989
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负责人:EBINA Yousuke
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依托单位:
Structure and the regulation of the gene expression of the human insulin receptor gene and its abnormalities
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批准号:61480131
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$3.97万
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财政年份:1986
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负责人:EBINA Yousuke
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依托单位:
海外基金