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Development of the visualization method of the stratum corneum barrier function by Time-of-Flight Secondary Ion Mass Spectroscopy (TOF-SIMS)

Development of the visualization method of the stratum corneum barrier function by Time-of-Flight Secondary Ion Mass Spectroscopy (TOF-SIMS)
开发利用飞行时间二次离子质谱(TOF-SIMS)的角质层屏障功能可视化方法
批准号:
23659555
负责人:
KUBO Akiharu
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

项目摘要

项目成果

KUBO Akiharu的其他基金

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中文摘要
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英文摘要
The stratum corneum (SC), the outermost barrier of mammalian bodies, consists of layers of cornified keratinocytes with intercellular spaces sealed with lipids. The insolubility of the SC has hampered in-depth analysis, and the SC has been considered a ho
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会议论文
Surface barrier and immunology of the skin.
皮肤的表面屏障和免疫学。
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Kubo A, Ishizaki I, Kubo A, Kawasaki H, Ohashi Y, and Amagai M, Kubo A, Kubo A, Kubo A, Kubo A]
通讯作者: Kubo A
The stratum corneum comprises three layers with distinct barrier properties, as revealed by TOF-SIMS imaging.
TOF-SIMS 成像显示,角质层由三层组成,具有不同的屏障特性。
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Kubo A, Ishizaki I, Kubo A, Kawasaki H, Ohashi Y, and Amagai M]
通讯作者: and Amagai M
TOF-SIMSによるマウス皮膚組織の深さ方向分析
TOF-SIMS 小鼠皮肤组织深度分析
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [石崎逸子, Hammond J S, Bryan S R, 久保亮治, 山本公]
通讯作者: 山本公
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Kubo A, Ishizaki I, Kubo A, Kawasaki H, Ohashi Y, and Amagai M, Kubo A, Kubo A, Kubo A, Kubo A, Kubo A]
通讯作者: Kubo A
14
    Evaluation of the tight junction barrier impairment in the pathogenesis of atopic dermatitis
    • 批准号:
      25670507
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2013
    • 负责人:
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    Analysis of the dynamic skin immune and physical barrier system by tight junctions and Langerhans cells
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    • 财政年份:
      2010
    • 负责人:
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    The analysis of centrosome replication cycle in Bowen's disease
    • 批准号:
      20591330
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.16万
    • 财政年份:
      2008
    • 负责人:
      KUBO Akiharu
    • 依托单位: