Development of molecular target radiation therapy from molecular target imaging

本研究是一项尝试，以开发一种新的概念，使分子靶向药物的癌症，使放射治疗。这一概念不仅可以允许分子靶向成像，还可以允许分子靶向放射治疗。在这项研究中，我们使用我们的新的分子成像化合物，PYK的EGFR-TK。该化合物具有用于EGFR-TK的体内成像的巨大潜力。总之，尽管需要额外的化合物来改善靶向摄取或靶向与非靶向的比率，但分子靶向放射治疗是可能实现的。

This study is a trial to develop a novel concept which makes molecular target drug for cancer enable radiation therapy . This concept can allow not only molecular target imaging and also molecular target radiation therapy. In this study, we use our new molecular imaging compound, PYK for EGFR-TK. This compound has a great potential for in vivo imaging for EGFR-TK. In conclusion, molecular target radiation therapy might be achieved although additional compounds are required to improve target uptake or target to non-target ratio.