Analysis of molecular forces for stem/progenitor cell homing in bone regeneration

在牵张成骨中，SDF-1在新生血管网络的重建中起着至关重要的作用。SDF-1的抑制减少了牵张间隙的血流量。再由膜性骨化型变为软骨内骨化型。另一方面，SDF-1过表达实验的实验结果，为应用迁移细胞系统促进组织再生的可能性提供了一种新的医疗装置。

In distraction osteogenesis, SDF-1 plays an essential role in the reconstruction of the neovascular network. Blood flow in the distraction gap is reduced by SDF-1 suppression. Then, it was changed to endochondral ossification style from membranous ossification style. On the other hand, experimental results on SDF-1 over-expression experiments, possibilities to promote tissue regeneration by applying the migration cell system, a new medical device provided was suggested.