The molecular epidemiologic analysis of the mechanism of calculus formation: Role of the bacteria exist in saliva

Matruchotii棒杆菌在生物膜的钙化过程中起着重要作用。然而，由于目前还没有建立一种简单的免疫学检测方法来研究马氏贾第鞭毛虫与肾结石沉积的关系，因此，本研究的目的是寻找一种马氏狸殖吸虫的特异性抗原。该抗原为免疫学检测方法的建立奠定了基础。本研究分离了20种不同类型的马氏囊尾藻钙结合膜蛋白。这些膜蛋白可分为酸性蛋白。

Corynebacterium matruchotii plays an important role in calcification of the biofilm. However, there are few epidemiological survey and clinical data in the association between C. matruchotii and carculus deposition.Because, a simple immunological detection method of C. matruchotii has not been developed.In this study, we aimed to find a specific antigen of C. matruchotii. The antigen will work for development of an immunological detection method.Twenty types of calcium-binding membrane proteins of C. matruchotii were isolated in this study. Those membrane proteins can be classified into acid proteins.