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Axonal regeneration via regulation of point contacts

Axonal regeneration via regulation of point contacts
通过点接触调节轴突再生
批准号:
23700376
负责人:
KUBOYAMA TOMOHARU
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

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中文摘要
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英文摘要
I previously clarified that enhancing of point contact dynamics promoted axonal regeneration in cultured system that mimicked failure of axonal regeneration in the injured central nervous system. In this study, I showed that protein kinase A, p21-activated kinase and paxillin were involved in the above regeneration mechanisms. This study proposes novel targets for axonal regeneration in spinal cord injury, etc.
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会议论文
Screening on functions from some Chinese herbs for spinal cord injury.
部分中药治疗脊髓损伤的作用筛选.
DOI: --
发表时间: 2012
期刊: Chinese Journal of Experimental Traditional Medical Formulae
影响因子: --
作者: [Wang XH, Zhu H, Konno K, Tohda C, Kazuma K, Kuboyama T, Miyanaga S]
通讯作者: Miyanaga S
Improvement of motor dysfunction in acute and chronic phases in spinal cord injury mice by a crude drug-derived compound.
通过生药衍生化合物改善脊髓损伤小鼠急性期和慢性期的运动功能障碍。
DOI: --
发表时间: 2014
期刊:
影响因子: --
作者: [Tanabe N., Kuboyama T., Kazuma K., Konno K., Tohda C.]
通讯作者: Tohda C.
DR improves memory impairment in Alzheimer's disease model mice, 5XFAD, and attenuates amyloid β-induced axonal atrophy
DR 改善阿尔茨海默病模型小鼠 5XFAD 的记忆障碍,并减轻β淀粉样蛋白诱导的轴突萎缩
DOI: --
发表时间: 2014
期刊:
影响因子: --
作者: [Yang Z., Kuboyama T., Tohda C.]
通讯作者: Tohda C.
Signal transduction underlying chondroitin sulfate proteoglycan-mediated inhibition of axon regeneration
硫酸软骨素蛋白聚糖介导的轴突再生抑制作用的信号转导
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Kuboyama T, Silver J, Tohda C, Kamiguchi H]
通讯作者: Kamiguchi H
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