Relationship between arterial stiffness and the oxyhemoglobin signal during cycling exercise at different intensities

近红外光谱(NIRS)是一种广泛使用的基于脑血流动力学响应的无创测量人脑活动的方法。近红外光谱使研究人员能够可视化人类步态中的皮质激活模式。然而，系统变化会影响测量的信号。我们确定了在动态运动过程中近红外信号与皮肤血流量(SBF)或血压的关系。健康志愿者参与了这项研究。脉搏波速度在正常范围。受试者在30%、50%和70%VO2峰值负荷下在自行车功率计上进行运动时，测量氧合血红蛋白信号(O2Hb)、SBF和平均动脉压(MAP)。运动过程中，VO2、VCO2、HR、MAP、SBF随负荷增加而增加。而O2Hb在70%VO2高峰期下降。

Near-infrared spectroscopy (NIRS) is a widely used non-invasive method to measure human brain activation based on cerebral hemodynamic response. NIRS has allowed researchers to visualize cortical activation patterns during human gait. However, systemic changes influence the measured signals. We determined the relationship between NIRS signals and skin blood flow (SBF) or blood pressure during dynamic movement. Healthy volunteers participated in this study. The pulse wave velocity was normal range. The oxyhemoglobin signal (O2Hb), SBF, and mean arterial pressure (MAP) were measured while the subjects performed exercise on a cycle ergometer at workloads corresponding to 30%, 50%, and 70% VO2peak. During the exercise, VO2, VCO2, HR, MAP and SBF were increased with increasing load on the cycle ergometer. However, O2Hb decreased during 70% VO2peak.