Methods for the bottom-up reconstruction of gene-regulatory networks
Methods for the bottom-up reconstruction of gene-regulatory networks
批准号:
23710235
负责人:
DIEGO Miranda-saavedra
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
Development of the best computational method for enhancer detection, capable of identifying enhancers from ChIP-chip and ChIP-seq libraries with a better comparative performance than other published methods for enhancer prediction (Fernandez and Miranda-Saavedra, 2012).Development of a novel method for the reconstruction of Transcriptional Regulatory Modules (TRMs) (Hutchins et al, 2013).The above methods have provided new and fundamental insights into the STAT3 controlled anti-inflammatory response network (Hutchins et al, Blood, 2012; Hutchins et al, JAK-STAT, 2013).
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DOI:
10.4161/jkst.25097
发表时间:
2013-10-01
期刊:
JAK-STAT
影响因子:
--
作者:
[Hutchins AP, Diez D, Miranda-Saavedra D]
通讯作者:
Miranda-Saavedra D
Genome-wide Enhancer Predictions from Chromatin Methylation Marks using Genetic Algorithm-Optimised Support Vector Machines.
使用遗传算法优化的支持向量机根据染色质甲基化标记进行全基因组增强子预测。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Marty Kwok-Shing Wong, Haruka Ozaki, Yutaka Suzuki, Wataru Iwasaki, and Yoshio Takei., 日野信次朗, Diego Miranda-Saavedra]
通讯作者:
Diego Miranda-Saavedra
Prediction of the effectors of the anti-inflammatory response by ChIP-seq and RNA-seq analysis.
通过 ChIP-seq 和 RNA-seq 分析预测抗炎反应的效应器。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Shotaro Hirase, Haruka Ozaki, and Wataru Iwasaki., Diego Miranda-Saavedra.]
通讯作者:
Diego Miranda-Saavedra.
DOI:
10.1093/nar/gks149
发表时间:
2012-05
期刊:
Nucleic acids research
影响因子:
14.9
作者:
[Fernández M, Miranda-Saavedra D]
通讯作者:
Miranda-Saavedra D
Control of the anti-inflammatory response by STAT3.
STAT3 控制抗炎反应。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Mio Takeuchi, Yoichi Kamagata, Kenshiro Oshima, Satoshi Hanada, Hideyuki Tamaki, Katsumi Marumo, Hiroto Maeda, Munetomo Nedachi, Masahira Hattori, Wataru Iwasaki, and Susumu Sakata., Diego Miranda-Saavedra]
通讯作者:
Diego Miranda-Saavedra
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