Production of a novel blistering disease model by regulating expression of collagen XVII
Production of a novel blistering disease model by regulating expression of collagen XVII
批准号:
24390274
负责人:
Nishie Wataru
金额:
$11.48万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2016-03-31
中文摘要
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英文摘要
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Antibodies to pathogenic epitopes on type XVII collagen cause skin fragility in a complement-dependent and -independent manner
XVII 型胶原上致病性表位的抗体以补体依赖性和非补体依赖性方式导致皮肤脆性
DOI:
--
发表时间:
2012
期刊:
J Immunol
影响因子:
4.4
作者:
[Natsuga K, Nishie W, et. Al]
通讯作者:
et. Al
Detection of pathological cleavage sites and neoepitopes on collagen XVII, a major autoantigen for bullous pemphigoid.
检测胶原蛋白 XVII(大疱性类天疱疮的主要自身抗原)上的病理裂解位点和新表位。
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Nishie W, Ujiie H, Izumi K, Shimizu H]
通讯作者:
Shimizu H
Context-dependent tight regulation of collagen XVII ectodomain shedding in skin.
皮肤中胶原蛋白 XVII 胞外域脱落的环境依赖性严格调节。
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Nishie W, Natsuga K, Izumi K, Ujiie H, Hata H, Nakamura H, Shimizu H]
通讯作者:
Shimizu H
Shedding of the type VII collagen
VII 型胶原蛋白的脱落
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Takasaki Y, Koide T, Wang C, Kimura H, Xing J, Kushima I, Ishizuka K, Mori D, Sekiguchi M, Ikeda M, Aizawa M, Tsurumaru N, Iwayama Y, Yoshimi A, Arioka Y, Yoshida M, Noma H, Oya-Ito T, Nakamura Y, Kunimoto S, Aleksic B, Uno Y, Okada T, Ujike H, Egawa J, K, Nishie W]
通讯作者:
Nishie W
Neoepitopes on the modifiedamino-terminus of the shed ectodomain of collagen XVII
XVII 胶原脱落胞外域修饰氨基末端的新表位
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Nishie W, Ujiie H, Shinkuma S, Bruckner-Tuderman L, Shimizu H]
通讯作者:
Shimizu H
共 6 条
Production of blistering disease model by regulating collagen XVII expression.(Fostering Joint International Research)
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批准号:15KK0289
-
项目类别:Fund for the Promotion of Joint International Research (Fostering Joint International Research)
-
资助金额:$9.15万
-
财政年份:2016
-
负责人:Nishie Wataru
-
依托单位:
Novel bullous pemphigoid models induced by breaking tolerance to autoantigens.
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批准号:16H05365
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.15万
-
财政年份:2016
-
负责人:Nishie Wataru
-
依托单位:
Pathogenesis of bullous pemphigoid: a study using class-switched monoclonal antibodies.
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批准号:16K15539
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.16万
-
财政年份:2016
-
负责人:Nishie Wataru
-
依托单位:
Induction of tolerance to bullous pemphigoid autoantigen by oral administration of antigenic peptides.
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批准号:15K15409
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2015
-
负责人:Nishie Wataru
-
依托单位: