A novel strategy for heart failure by anti-aging

抗衰老治疗心力衰竭的新策略

• 批准号: 24591100
• 负责人: TAKEISHI Yasuchika
• 金额: $ 3.41万
• 依托单位: Fukushima Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24591100/
• 关键词: SMP30; doxorubcin; oxidative stress; signal transduction; heart failure; ROS; NADPH; 加齢; 心不全; 酸化ストレス; ドキソルビシン; アポトーシス; 遺伝子操作マウス

项目成果

Long pentraxin PTX3 exacerbates pressure overload-induced left ventricular dysfunction.

• DOI: 10.1371/journal.pone.0053133
• 发表时间: 2013
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Suzuki S;Shishido T;Funayama A;Netsu S;Ishino M;Kitahara T;Sasaki T;Katoh S;Otaki Y;Watanabe T;Shibata Y;Mantovani A;Takeishi Y;Kubota I
• 通讯作者: Kubota I

Impairment of FOS mRNA stabilization following translation arrest in granulocytes from myelodysplastic syndrome patients.

• DOI: 10.1371/journal.pone.0061107
• 发表时间: 2013
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Feng X;Shikama Y;Shichishima T;Noji H;Ikeda K;Ogawa K;Kimura H;Takeishi Y;Kimura J
• 通讯作者: Kimura J

Deficiency of senescence marker protein 30 exacerbates angiotensin II-induced cardiac remodelling

衰老标记蛋白 30 的缺乏会加剧血管紧张素 II 诱导的心脏重塑

• DOI: 10.1093/cvr/cvt122
• 发表时间: 2013
• 期刊: Cardiovascular Research
• 影响因子: 10.8
• 作者: Misaka T;Suzuki S;Miyata M;Kobayashi A;Shishido T;Ishigami A;Saitoh S;Hirose M;Kubota I;Takeishi Y
• 通讯作者: Takeishi Y

Liver dysfunction assessed by model of end-stage liver disease excluding INR (MELD-XI) scoring system predicts adverse prognosis in heart failure

通过不包括 INR (MELD-XI) 评分系统的终末期肝病模型评估肝功能障碍可预测心力衰竭的不良预后

• 作者: Shimizu T;Yoshihisa A;Takiguchi M;Yamauchi H;Owada T;Iwaya S;Miyata M;Sato T;Suzuki S;Oikawa M;Kobayashi A;Yamaki T;Sugimoto K;Kunii H;Nakazato K;Suzuki H;Saitoh S;Takeishi Y
• 通讯作者: Takeishi Y

Severity of airflow limitation predicts exercise capacity and adverse clinical outcomes in chronic heart failure

气流受限的严重程度可预测慢性心力衰竭的运动能力和不良临床结果

• 作者: Sato T;Yamauchi H;Kanno Y;Suzuki S;Yoshihisa A;Sugimoto K;Yamaki T;Kunii H;Nakazato K;Suzuki H;Saitoh S;Takeishi Y
• 通讯作者: Takeishi Y