Elucidation of molecular mechanisms in pain-emotion system for chronic pain and applicatiopn of BDNF treatment
Elucidation of molecular mechanisms in pain-emotion system for chronic pain and applicatiopn of BDNF treatment
批准号:
24593057
负责人:
ISHIKAWA Toshizo
金额:
$3.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2015-03-31
中文摘要
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英文摘要
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4-Methylcatechol, an inducer of brain derived neurotrophic factor, ameliorates pain-related negative emotion by preventing the ERK/CREB signaling pathway anterior cingulated cortex
4-甲基儿茶酚是脑源性神经营养因子的诱导剂,通过阻止 ERK/CREB 信号通路前扣带皮层来改善疼痛相关的负面情绪
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Y Iwanaga, K Fukuhara, S Yasuda, Y Ariyoshi, T Ibuki, S Okuyama, Y Furukawa, J Ishikawa, T Ishikawa]
通讯作者:
T Ishikawa
Reconfirmation of interaction between monoaminergic neuron and BDNF in RVM with Lmipramine for reducing depression related to chronic pain
再次证实 RVM 中单胺能神经元和 BDNF 与左米帕明的相互作用可减少与慢性疼痛相关的抑郁
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[S Yasuda, T Kakeda, Y Ida, H Yamagata, Y Iwanaga, S Sonoda, H Suzuki, T Ibuki, T Ishikawa]
通讯作者:
T Ishikawa
ラット神経障害性疼痛に対する4-Methylcatecholの効果―細胞内シグナルによる評価
4-甲基儿茶酚对大鼠神经病理性疼痛的影响——细胞内信号评估
DOI:
--
发表时间:
2012
期刊:
日本歯科麻酔学会誌
影响因子:
--
作者:
[松本吉洋, 石川浩三, 福原佳世子, 安田聖子, 吉田充広, 仲西 修, 石川敏三]
通讯作者:
石川敏三
4-Methylcathechol, neurotorophin inducer, prevents abnormal pain-emotion response including hypersensitization and mood disorder in rat with chronic pain
4-甲基儿茶酚(神经托啡诱导剂)可预防慢性疼痛大鼠的异常疼痛情绪反应,包括过敏和情绪障碍
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[M Yoshida, S Yasuda, S Minoda, K Ishikawa, S Yamamoto, Y Kishishita, S Watanabe, O Nakanishi, T Ishikawa]
通讯作者:
T Ishikawa
Spinal cord injury 1. Basic Concepts of Pathophysiological Mechanisms
脊髓损伤 1.病理生理机制的基本概念
DOI:
--
发表时间:
2013
期刊:
Current Pharmaceutical Design
影响因子:
3.1
作者:
[Ishikawa T, Suzuki H,Ishikawa K,Yasuda S, Kakeda T]
通讯作者:
Kakeda T
共 26 条
The targeting treatment for prevention and restoration in patients with neuro-degenerative disease
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批准号:20592374
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.16万
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财政年份:2008
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负责人:ISHIKAWA Toshizo
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依托单位:
Regenerations of Spinal Neurons and its Sensory Function in Pathological Pain following Peripheral Nerve Injury
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批准号:15390475
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.29万
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财政年份:2003
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负责人:ISHIKAWA Toshizo
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依托单位:
Regenerations of Spinal Cord Neurons and its Sensory Function in Pathological Pain following Peripheral Nerve Injury
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批准号:13470321
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.18万
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财政年份:2001
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负责人:ISHIKAWA Toshizo
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依托单位:
Elucidation of Molecular and Neurobiological Mechanism in Pathophysiological Pain following Peripheral Injury
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批准号:10470318
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.95万
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财政年份:1998
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负责人:ISHIKAWA Toshizo
-
依托单位:
Elucidation of Molecular Mechanisms of Pain : Role of PKC and NGF on spinal sensitization in the pathological state following peripheral tissue injury
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批准号:06454444
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$2.82万
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财政年份:1994
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负责人:ISHIKAWA Toshizo
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依托单位:
海外基金