The influences to postoperative quality of life, due to perioperative analgesia

围手术期镇痛对术后生活质量的影响

• 批准号: 24791611
• 负责人: ASAKURA Ayako
• 金额: $ 2.66万
• 依托单位: Yokohama City University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24791611/
• 关键词: 術後回復の質

The objective of this study was to evaluate the influences to postoperative quality of life, due to perioperative analgesia.In open hepatectomy, an invasive surgery, subjects were randomized to receive remifentanil or epidural anesthesia as perioperative analgesia. Transaminase, inflammation marker, and quality of life were investigated. There were not much significant differences between groups.In renal or ureteral laparoscopic surgery, a less-invasive surgery, subjects were randomized to receive fentanyl or remifentanil for perioperative analgesia. Release of stress hormone and inflammation marker during surgery, quality of recovery and quality of life after surgery were investigated. The quality of recovery and quality of life tend to be better in fentanyl group.

本研究的目的是评估围手术期镇痛对术后生活质量的影响，在开放性肝切除术中，受试者随机接受瑞芬太尼或硬膜外麻醉作为围手术期镇痛。观察转氨酶、炎症指标及生活质量。组间差异不大。在肾脏或输尿管腹腔镜手术（一种微创手术）中，受试者被随机分配接受芬太尼或瑞芬太尼进行围手术期镇痛。观察两组患者术中应激激素和炎症标志物的释放、术后恢复质量和生活质量。芬太尼组的恢复质量和生活质量有改善的趋势。

项目成果

Which Provides Better Postoperative Recovery After Laparoscopic Surgery, Fentanyl or Remifentanil?

腹腔镜手术后，芬太尼或瑞芬太尼哪个能提供更好的术后恢复？

• 发表时间: 2014
• 作者: Ayako Asakura;Takahiro Mihara;Takahisa Goto
• 通讯作者: Takahisa Goto