The influences to postoperative quality of life, due to perioperative analgesia

本研究的目的是评估围手术期镇痛对术后生活质量的影响。在开腹肝切除术中，受试者随机接受瑞芬太尼或硬膜外麻醉作为围手术期镇痛。观察转氨酶、炎症标志物和生活质量的变化。在肾或输尿管腹腔镜手术中，受试者随机接受芬太尼或瑞芬太尼用于围手术期镇痛。观察术中应激激素和炎症标志物的释放、术后恢复质量和生活质量。芬太尼组的康复质量和生活质量较好。

The objective of this study was to evaluate the influences to postoperative quality of life, due to perioperative analgesia.In open hepatectomy, an invasive surgery, subjects were randomized to receive remifentanil or epidural anesthesia as perioperative analgesia. Transaminase, inflammation marker, and quality of life were investigated. There were not much significant differences between groups.In renal or ureteral laparoscopic surgery, a less-invasive surgery, subjects were randomized to receive fentanyl or remifentanil for perioperative analgesia. Release of stress hormone and inflammation marker during surgery, quality of recovery and quality of life after surgery were investigated. The quality of recovery and quality of life tend to be better in fentanyl group.