Research of oxidative stress and mitochondrial gene polymorphism in presbycusis
Research of oxidative stress and mitochondrial gene polymorphism in presbycusis
批准号:
24791802
负责人:
SHIMAMOTO Kirito
金额:
$2.25万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31
中文摘要
包括线粒体12SrRNA在内的13个基因OXHOS位点在老年性耳聋组中有统计学意义。另一方面,BAP值与年龄成比例较低(平均833纳米mol/l),与SNP无关。在SNP的背景下也没有观察到- rom值。由于也有地震的影响,门诊就诊的患者数量减少,可作为目标的病例数量有所减少,确保受试者数量少于预期。在研究过程中也有一些影响到一个个地震目标的方向,也有明显的失败的生命原因,在未来,我们希望支持作为重要事项的目标,以确保在农村地区的研究体系。
英文摘要
13 genes OXHOS site at the construction area, including the mitochondrial 12SrRNA was statistically significant in presbycusis group. On the other hand, BAP values were found low levels of BAP values (average 833 nano mol/l) in proportion to age, there was no correlation with the SNP. d-ROM value was also not observed in the context of the SNP as well.Because there is the influence of the earthquake also, a decrease in outpatient visits number of patients, cases that can be a target has been reduced, ensuring the number of subjects was less than expected. There is also some influence in the research process one by one earthquake in the direction of the target, and also conspicuous failure of the life of the cause, in the future, we would like to support as important matters to ensure the target in rural areas along with the research system .
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
老人性難聴に関するミトコンドリア遺伝子と酸化ストレスの検討
与老年性耳聋相关的线粒体基因和氧化应激检查
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[竹井 慎, 荒井 潤, 保富宗城, 山中 昇, 玉川 俊次, 玉川俊次, 嶋本記里人]
通讯作者:
嶋本記里人