Searching the drugs for recurrent corneal erosion by evaluating the corneal epithelial adhesion ability

用实验动物建立了角膜上皮细胞黏附能力评价模型，糖尿病组和对照组角膜上皮细胞黏附能力分别为24.9~13.4g和33.2~18.9g，但糖尿病组和对照组之间无显著差异，如果改进实验方法，可以在体内对角膜上皮细胞黏附能力进行定量评价。此外，该系统还可用于研制角膜上皮伤口愈合滴眼液。

We were able to build an evaluation model of the corneal epithelium adhesion ability using the laboratory animal.Measuring corneal epithelium adhesion ability with diabetes group and control group, it was 24.9+-13.4 g and 33.2+-18.9 g. But there was no significant difference between diabetes group and control group.If the experimental procedure is improved, we are able to know a quantitative evaluation of the corneal epithelium adhesion ability in in vivo. In addition, this system will be useful to develop the corneal epithelial wound healing eye drops.