Development of oxidation reaction system using vesicles as generation site of singlet oxygen

以含锑四苯基卟啉配合物的磷脂微囊为原料，建立了有机底物可见光光氧化反应体系。含轴向烷基配体的Sb络合物以较高的结合常数吸附在囊泡上。以9，10-二甲基蒽酮为目标分子，研究了其光氧化反应，并对反应机理进行了分析。当Sb络合物和靶共存于一个囊泡中时，氧化反应通过光诱导电子转移有效地进行。当两者分别存在于囊泡上时，反应通过生成单线态氧进行。

Photooxydation reaction system for organic substrates by visible-light irradiation were developed from phospholipid vesicles containing antimony tetraphenylporphyrin complexes. Sb complexes containing axial alkyl ligand adsorbed on the vesicles with a high binding constants. Photooxidation reaction of 9,10-dimethylanthrathen as a target molecule was studied and the reaction mechanism was analyzed. When the Sb complex and the target coexisted in one vesicle, the oxidation reaction proceed efficiently via photoinduced electron transfer. When both were existed on vesicles separately, the reaction proceed via generation of singlet oxygen.