Basic and clinical study on inhibitory modulation of motor function using a regulatory focal brain cooling
Basic and clinical study on inhibitory modulation of motor function using a regulatory focal brain cooling
批准号:
24700420
负责人:
IMOTO HIROCHIKA
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31
中文摘要
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英文摘要
The neurosurgical treatment for diseases such as intractable epilepsy and brain tumors, functional localization of the brain is evaluated by functional brain mapping. However, There is a problem such as accidentally induced convulsion by electrical stimulation. In this study, we investigated the effects on brain function by focal brain cooling.As a result, the boundary of the cooling temperature to cause dysfunction, was 10-15 degC. Further, if the cooling at 15 degC does not cause loss of function, brain function was not disrupted. Therefore, the focal brain cooling is reversible brain function control method could be confirmed.
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Changes in glutamate concentration, glucose metablism, and cerebral blood flow during focal brain cooling of the epileptogenic cortex in humans
人类致痫皮层局灶性脑冷却过程中谷氨酸浓度、葡萄糖代谢和脑血流量的变化
DOI:
--
发表时间:
2014
期刊:
Epilepsia
影响因子:
5.6
作者:
[Sadahiro Nonura, Masami Fujii, Takao Inoue,Yeting He, Yuichi Maruta, Hiroyasu Koizumi, Eiichi Suehiro, Hirochika Imoto, Hideyuki Ishihara, Fumiaki Oka, Mishiya Matsumoto, Yuji Owada, Takeshi Yamakawa, and Michiyasu Suzuki]
通讯作者:
and Michiyasu Suzuki
当科における長期脳波ビデオモニタリングの記録と解析における工夫
我科长期脑电视频监测记录和分析的改进
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[丸田雄一, 藤井正美, 井本浩哉, 野村貞宏, 五島久陽, 田中信宏, 貞廣浩和, 末廣栄一, 米田 浩, 鈴木倫保]
通讯作者:
鈴木倫保
機能神経外科の新たなアプローチ:Thermal neuromodulation
功能神经外科的新方法:热神经调节
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[藤井正美, 井上貴雄, 賀業霆, 丸田雄一, 井本浩哉, 田中信宏, 奥高行, 藤岡裕士, 米田浩, 小泉博靖, 野村貞宏, 鈴木倫保, 山川烈]
通讯作者:
山川烈
痙縮に対する脊髄刺激療法の効果
脊髓刺激疗法对痉挛的影响
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[井本浩哉, 藤井正美, 丸田雄一, 野村貞宏, 鈴木倫保]
通讯作者:
鈴木倫保
DOI:
10.1111/epi.12600
发表时间:
2014-05-01
期刊:
EPILEPSIA
影响因子:
5.6
作者:
[Nomura, Sadahiro, Fujii, Masami, Suzuki, Michiyasu]
通讯作者:
Suzuki, Michiyasu
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