Association between daily physical activity and immunological function in older individuals

本研究的目的是研究老年人日常身体活动的最佳水平和时间，以维持免疫功能。所有受试者均独立生活。为了评估中高强度体力活动的步数和时间，所有受试者连续1年佩戴带有单轴加速度计的计步器（Lifecorder, Kenz, Nagoya）。测定静息状态下唾液分泌免疫球蛋白A和中性粒细胞吞噬功能。结果表明，嗜中性粒细胞吞噬功能与步数显著相关（p<0.05）。唾液分泌免疫球蛋白A与步数和中高强度体力活动时间显著相关（p<0.05）。这些结果表明，习惯性体育活动对维持老年人免疫功能具有重要作用。

The purpose of the present investigation was to examine the optimal levels and timings of daily physical activity to maintain immunological function in older individuals. All subjects were independently living. In order to assess the number of steps and the time for moderate to vigorous intensity physical activity, all subjects wore a pedometer with one-axial accelerometer (Lifecorder, Kenz, Nagoya) continuously for 1 year. We assessed the salivary secretory immunoglobulin A and the neutrophil phagocytosis function at the resting condition. As results, the neutrophil phagocytosis function significantly associated with the number of step counts (p<0.05). The salivary secretory immunoglobulin A significantly associated with both the number of step counts and the time for moderate to vigorous intensity physical activity (p<0.05). These results indicate that the habitual physical activity have important role to maintain the immunological functions in older individuals.