IL-1 beta induced vascular endothelial markers in HFD

HFD 中 IL-1β 诱导的血管内皮标志物

• 批准号: 25505005
• 负责人: Shirafuji Naoki
• 金额: $ 3.33万
• 依托单位: Teikyo University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2013
• 资助国家: 日本
• 起止时间: 2013-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25505005/
• 关键词: 皮膚線維芽細胞; インターロイキン１ベータ; 血管内皮前駆細胞; CD34; CD41; CD31; CD45; IL-1 beta; HSC; myofibroblast; HDF; human dermal fibroblast; hematopoietic stem cell; Interleukin-1; VEGF-A; poly I:C; electrical stimulation; ヒト皮膚線維芽細胞; 造血幹細胞; 脱分化; interleukin

项目成果

Hemogenic endothelium-like changes were observed in an adult human dermal fibroblast with an electrical stimulation.

在电刺激的成人真皮成纤维细胞中观察到造血内皮样变化。

• 发表时间: 2015
• 作者: Ritsu Sumiyoshi;Takuji Matsuo;Ryosuke Shirasaki;Yoko Oka-Miura;Tadashi Yamamoto;Kennsuke Matsumoto;Jun Ooi;Nobu Akiyama;Kazuo Kawasugi;Naoki Shirafuji.
• 通讯作者: Naoki Shirafuji.

Hemogenic endothelium-like changes were observed in an adult human dermal fibroblast with poly (I:C) culture and an electrical stimulation

通过聚 (I:C) 培养和电刺激，在成人真皮成纤维细胞中观察到造血内皮样变化

• 发表时间: 2015
• 作者: Takuji Matsuo;Rhitsu Sumiyoshi;Ryosuke Shirasaki;Yoko Oka-Miura;Tadashi Yamamoto;Kennsuke Matsumoto;Jun Ooi;Naoki Shirafuji.
• 通讯作者: Naoki Shirafuji.

Hemogenic endothelium-like changes were derived to an adult human dermal fibroblast by electrical stimulation

通过电刺激对成人真皮成纤维细胞产生造血内皮样变化

• 发表时间: 2014
• 作者: Takuji Matsuo;Ryosuke Shirasaki;Yoko Oka;Tadashi Yamamoto;Kennsuke Matsumoto;Jun Ooi;Naoki Shirafuji.
• 通讯作者: Naoki Shirafuji.

Biological effect of IL-1-beta to HDF for a long-term culture

IL-1-β 对长期培养的 HDF 的生物学效应

• 发表时间: 2016
• 作者: Rhitsu Sumiyoshi;Takuji Matsuo;Tadashi Yamamoto;Kennsuke Matsumoto;Jun Ooi;Kazuo Kawasugi;Naoki Shirafuji.
• 通讯作者: Naoki Shirafuji.

Adult human dermal fibroblasts was induced to express GATA-2 when they were cultured with interleukin 1-beta, erythropietin, and anti-human vascular endothelial growth factor-C antibody

用白细胞介素1-β、促红细胞生成素和抗人血管内皮生长因子-C 抗体培养成人真皮成纤维细胞，诱导其表达 GATA-2

• 发表时间: 2014
• 作者: Takuji Matsuo;Ryosuke Shirasaki;Yoko Oka;Kennsuke Matsumoto;Jun Ooi;and Naoki Shirafuji.
• 通讯作者: and Naoki Shirafuji.