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The underlying mechanism of glucocorticoid-regulated diurnal exacerbation of neuropathic pain hypersensitivity and its evaluation as a target of anti-allodynic drug

The underlying mechanism of glucocorticoid-regulated diurnal exacerbation of neuropathic pain hypersensitivity and its evaluation as a target of anti-allodynic drug
糖皮质激素调节的神经性疼痛超敏性昼夜加重的潜在机制及其作为抗异常疼痛药物靶点的评估
批准号:
15H04765
负责人:
Koyanagi Satoru
金额:
$9.73万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2015
资助国家:
日本
项目状态:
已结题
起止时间:
2015-04-01 至 2018-03-31

项目摘要

项目成果

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Chrono-omics analysis for exploring diagnostic and therapeutic target for neuropathic pain.
用于探索神经性疼痛诊断和治疗靶点的时间组学分析。
DOI: --
发表时间: 2017
期刊:
影响因子: --
作者: [Takara Watanabe, Hiroshi Muraishi, Ryoji Enomoto, Daisuke Kano, Mika Kagaya, Hideaki Katagiri, Tomohisa Uchida, Ryotaro Kondo, Tohru Takeda, Manobu Tanaka, Yoshihiro Nakagami, Fukushi Masahiro, Syota Hosokawa, Tatsuo Yoshida, Satoru Koyanagi]
通讯作者: Satoru Koyanagi
Chronopharmacological study of pregabalin for diabetic peripheral neuropathic pain
普瑞巴林治疗糖尿病周围神经病理性疼痛的时间药理学研究
DOI: --
发表时间: 2015
期刊:
影响因子: --
作者: [赤嶺孝祐, 和田恵里香, 楠瀬直喜, 橋本華, 谷口真理恵, 松永直哉, 小柳悟, 大戸茂弘]
通讯作者: 大戸茂弘
副腎皮質ホルモンによる脊髄細胞外への ATP放出と慢性痛の概日変動
肾上腺皮质激素诱导的脊髓细胞 ATP 释放和慢性疼痛的昼夜节律波动
DOI: --
发表时间: 2017
期刊:
影响因子: --
作者: [Noothalapati Hemanth, Iwasaki Keita, Yoshimoto Chikako, Yoshikiyo Keisuke, Nishikawa Tomoe, Ando Masahiro, Hamaguchi Hiro-o, Yamamoto Tatsuyuki, 小柳 悟]
通讯作者: 小柳 悟
Molecular basis for circadian regulation of the intensity of cancer-derived pain in tumor-bearing mice
荷瘤小鼠癌源性疼痛强度昼夜节律调节的分子基础
DOI: --
发表时间: 2015
期刊:
影响因子: --
作者: [谷口真理恵, 小柳悟, 楠瀬直喜, 赤嶺孝祐, 松永直哉, 大戸茂弘]
通讯作者: 大戸茂弘
11
    Elucidation of the generation mechanism of cancer stem cells from circadian clock defective cells and development of strategy for overcoming of chemoresistance
    • 批准号:
      20K21484
    • 项目类别:
      Grant-in-Aid for Challenging Research (Exploratory)
    • 资助金额:
      $3.91万
    • 财政年份:
      2020
    • 负责人:
      Koyanagi Satoru
    • 依托单位:
    Integration analysis between RNA editing and circadian clock system for elucidation of interindividual variation of drug pharmacokinetics
    • 批准号:
      18H04019
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $21.88万
    • 财政年份:
      2018
    • 负责人:
      Koyanagi Satoru
    • 依托单位:
    Study on molecular mechanism for scaffold protein-regulated circadian localization of transporters on plasma membrane by
    • 批准号:
      17K19493
    • 项目类别:
      Grant-in-Aid for Challenging Research (Exploratory)
    • 资助金额:
      $3.99万
    • 财政年份:
      2017
    • 负责人:
      Koyanagi Satoru
    • 依托单位:
    Development of preventive strategy against oncogenesis by strengthening circadian clock function
    • 批准号:
      26670317
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.16万
    • 财政年份:
      2014
    • 负责人:
      Koyanagi Satoru
    • 依托单位:
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