Development of antibody-drug conjugate to diagnose and treat vulnerable plaque

开发抗体-药物偶联物来诊断和治疗易损斑块

• 批准号: 15H04821
• 负责人: MINAMINO TETSUO
• 金额: $ 10.57万
• 依托单位: Kagawa University (2016-2017)Osaka University (2015)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2015
• 资助国家: 日本
• 起止时间: 2015-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H04821/
• 关键词: HB-EGF抗体; HB-EGF抗体結合ベクター; 薬物送達; 不安定プラーク; 循環器・高血圧; HB-EGF; バイオテクノロジー

项目成果

Late Breaking Clinical Trials 2 (HF) : Low dose Erythropoietin in Patients with ST segment Elevation Myocardial Infarction (EPO AMI II Study): A Randomized Controlled Clinical Trial

最新突破性临床试验 2 (HF)：低剂量促红细胞生成素治疗 ST 段抬高型心肌梗死患者（EPO AMI II 研究）：一项随机对照临床试验

• 发表时间: 2017
• 作者: 南野哲男

Btg2 is a Negative Regulator of Cardiomyocyte Hypertrophy through a Decrease in Cytosolic RNA.

• DOI: 10.1038/srep28592
• 发表时间: 2016-06-27
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Masumura Y;Higo S;Asano Y;Kato H;Yan Y;Ishino S;Tsukamoto O;Kioka H;Hayashi T;Shintani Y;Yamazaki S;Minamino T;Kitakaze M;Komuro I;Takashima S;Sakata Y
• 通讯作者: Sakata Y

Development of a novel one-step production system for injectable liposomes under GMP

• DOI: 10.1080/10837450.2017.1290106
• 发表时间: 2018-01-01
• 期刊: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
• 影响因子: 3.4
• 作者: Araki, Ryo;Matsuzaki, Takashi;Minamino, Tetsuo
• 通讯作者: Minamino, Tetsuo

Targeted Therapy for Acute Autoimmune Myocarditis with Nano-Sized Liposomal FK506 in Rats.

• DOI: 10.1371/journal.pone.0160944
• 发表时间: 2016
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Okuda K;Fu HY;Matsuzaki T;Araki R;Tsuchida S;Thanikachalam PV;Fukuta T;Asai T;Yamato M;Sanada S;Asanuma H;Asano Y;Asakura M;Hanawa H;Hao H;Oku N;Takashima S;Kitakaze M;Sakata Y;Minamino T
• 通讯作者: Minamino T

Identification of the Mtus1 Splice Variant as a Novel Inhibitory Factor Against Cardiac Hypertrophy.

鉴定 Mtus1 剪接变体作为抗心脏肥大的新型抑制因子。

• DOI: 10.1161/jaha.116.003521
• 发表时间: 2016-07-06
• 期刊: Journal of the American Heart Association
• 影响因子: 5.4
• 作者: Ito S;Asakura M;Liao Y;Min KD;Takahashi A;Shindo K;Yamazaki S;Tsukamoto O;Asanuma H;Mogi M;Horiuchi M;Asano Y;Sanada S;Minamino T;Takashima S;Mochizuki N;Kitakaze M
• 通讯作者: Kitakaze M