Establishment of highly effective therapy for food allergy by concomitant use of kakkonto with oral immunotherapy
Establishment of highly effective therapy for food allergy by concomitant use of kakkonto with oral immunotherapy
批准号:
16K09234
负责人:
Yamamoto Takeshi
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2016
资助国家:
日本
项目状态:
已结题
起止时间:
2016-04-01 至 2019-03-31
中文摘要
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英文摘要
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Improvement of Therapeutic Efficacy of Oral Immunotherapy in Combination with Regulatory T Cell-Inducer Kakkonto in a Murine Food Allergy Model.
在鼠类食品过敏模型中,口服免疫疗法与调节性T细胞诱导剂Kakkonto结合使用的治疗功效提高。
DOI:
10.1371/journal.pone.0170577
发表时间:
2017
期刊:
PloS one
影响因子:
3.7
作者:
[Nagata Y, Yamamoto T, Hayashi M, Hayashi S, Kadowaki M]
通讯作者:
Kadowaki M
食物アレルギー病態モデルに対する葛根湯と経口免疫療法の併用療法によるレチノイン酸代謝酵素抑制を介した制御性T細胞の誘導.
在食物过敏病理模型中,通过 kakkonto 和口服免疫疗法的联合治疗抑制视黄酸代谢酶来诱导调节性 T 细胞。
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[長田夕佳, 山本 武, 門脇 真]
通讯作者:
門脇 真
経口免疫療法モデルマウスを用いた 葛根湯併用療法の寛解維持効果の検討
使用口服免疫疗法模型小鼠检查 Kakkonto 联合疗法的缓解维持效果
DOI:
--
发表时间:
2018
期刊:
影响因子:
--
作者:
[長田夕佳, 山本 武, 門脇 真]
通讯作者:
門脇 真
腸管制御性T細胞誘導能を持つ葛根湯と経口免疫療法の併用療法は食物アレルギー病態モデルでの治療効果を亢進させる.
具有诱导肠道调节性T细胞能力的Kakkonto与口服免疫疗法的联合治疗可增强食物过敏病理模型的治疗效果。
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[長田夕佳, 山本 武, 林美智慧, 門脇 真.]
通讯作者:
門脇 真.
マウス食物アレルギー病態モデルを用いて新たに見出した葛根湯併用経口免疫療法の根本的治療法としての提案
以小鼠食物过敏病理模型为基础治疗方法,提出与 kakkonto 相结合的新型口服免疫疗法
DOI:
--
发表时间:
2018
期刊:
影响因子:
--
作者:
[Kano M, Muratsubaki T, Van Oudenhove L, Morishita J, Yoshizawa M, Kohno K, Yagihashi M, Tanaka Y, Mugikura S, Dupont P, Ly HG, Takase K, Kanazawa M, Fukudo S., 山本 武]
通讯作者:
山本 武
共 16 条
Unraveling the cooperative action of p53 and autophagy against kidney aging
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财政年份:2021
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依托单位:
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依托单位:
A study on effect of surface roughness for friction force and surface damage under squeeze motion
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批准号:19K04155
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:2019
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负责人:Yamamoto Takeshi
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依托单位:
Induction of tolerance by concomitant use of kakkonto with oral immunotherapy and exploration of candidate blood marker that enable evaluation of the effects of treatments for food allergy
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批准号:19K07908
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2019
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负责人:Yamamoto Takeshi
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依托单位:
Novel treatment of arrhythmia and heart failure by controlling the domain of ryanodine receptors
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批准号:18K08108
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2018
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负责人:Yamamoto Takeshi
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依托单位:
Dynamic Induction of Single-Handed Helix by Chiral Guests to Macromolecular Chiral Catalysts with Amplification of Homochirality
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资助金额:$2.66万
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财政年份:2018
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负责人:Yamamoto Takeshi
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依托单位:
mplementing interprofessional education at higher educational institutions in Japan
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批准号:17K08920
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2017
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负责人:Yamamoto Takeshi
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依托单位:
Elucidation of the translocation mechanism of M. pneumoniae across the human bronchial epithelial barrier.
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批准号:16K19619
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
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财政年份:2016
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负责人:Yamamoto Takeshi
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依托单位:
Strategies aimed at modulating autophagy for treating kidney diseases
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批准号:15H06371
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项目类别:Grant-in-Aid for Research Activity Start-up
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资助金额:$1.91万
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财政年份:2015
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负责人:Yamamoto Takeshi
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依托单位:
Asymmetric Synthesis of Dibenzohelicenes via Nickel-Catalyzed Intramolecular Cyclization of Triynes Using Helically Chiral Polymer Ligands
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负责人:Yamamoto Takeshi
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依托单位:
Anti-allergic effect of kakkonto by regulating intestinal mucosal immunity through the induction of regulatory T cells in the colon
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负责人:Yamamoto Takeshi
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依托单位: