Clarification of a role of sphingosine 1-phosphate in pathology of hepatocellular carcinoma, and its application for treatment strategy
Clarification of a role of sphingosine 1-phosphate in pathology of hepatocellular carcinoma, and its application for treatment strategy
批准号:
16K09343
负责人:
Ikeda Hitoshi
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2016
资助国家:
日本
项目状态:
已结题
起止时间:
2016-04-01 至 2019-03-31
中文摘要
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英文摘要
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DOI:
10.1038/srep32119
发表时间:
2016-08-26
期刊:
Scientific reports
影响因子:
4.6
作者:
[Sato M, Ikeda H, Uranbileg B, Kurano M, Saigusa D, Aoki J, Maki H, Kudo H, Hasegawa K, Kokudo N, Yatomi Y]
通讯作者:
Yatomi Y
Evidence Suggests Sphingosine 1-Phosphate Might Be Actively Generated, Degraded, and Transported to Extracellular Spaces With Increased S1P2 and S1P3 Expression in Colon Cancer.
有证据表明,随着结肠癌中 S1P2 和 S1P3 表达的增加,1-磷酸鞘氨醇可能会主动生成、降解并转运至细胞外空间。
DOI:
10.1016/j.clcc.2017.11.004
发表时间:
2017
期刊:
Clin Colorectal Cancer.
影响因子:
--
作者:
[Uranbileg B, Nishikawa T, Ikeda H, Kurano M, Sato M, Saigusa D, Aoki J, Watanabe T, Yatomi Y.]
通讯作者:
Yatomi Y.
DOI:
10.1371/journal.pone.0149462
发表时间:
2016
期刊:
PloS one
影响因子:
3.7
作者:
[Uranbileg B, Ikeda H, Kurano M, Enooku K, Sato M, Saigusa D, Aoki J, Ishizawa T, Hasegawa K, Kokudo N, Yatomi Y]
通讯作者:
Yatomi Y
The importance of S1P lyase in the pathophysiology of hepatocellular carcinoma and colon cancer.
S1P 裂解酶在肝细胞癌和结肠癌病理生理学中的重要性。
DOI:
--
发表时间:
2018
期刊:
影响因子:
--
作者:
[Uranbileg B, Ikeda H, Kurano M, Saigusa D, Kano K, Aoki J, and Yatomi Y.]
通讯作者:
and Yatomi Y.
S1P is actively metabolized and transported to extracellular spaces with increased receptors expression in colon cancer
S1P 在结肠癌中代谢活跃并转运至细胞外空间,受体表达增加
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Uranbileg B, Nishikawa T, Ikeda H, Kurano M, Sato M, Saigusa D, Aoki J, Watanabe T, Yatomi Y.]
通讯作者:
Yatomi Y.
海外基金