Clinical impact of viable circulating tumor cells (v-CTC) detection and PD-L1 expression on v-CTC in the patients with resectable pancreatic cancer

可切除胰腺癌患者中活循环肿瘤细胞 (v-CTC) 检测和 PD-L1 表达对 v-CTC 的临床影响

• 批准号: 16K10618
• 负责人: Tanemura Masahiro
• 金额: $ 3万
• 依托单位: Osaka University (2017-2018)Department of Clinical Research, National Hospital Organization Kure Medical Center (2016)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K10618/
• 关键词: 膵癌; 微小循環癌細胞; 腹腔内遊離癌細胞; テロメスキャン; バイオマーカー; 糖鎖; 糖鎖医薬; 創薬; オリゴデンドリマー

项目成果

Patients Treated with Preoperative Chemoradiation for Pancreatic Ductal Adenocarcinoma have Impaired Bone Density, a Predictor of Distant Metastasis.

接受术前放化疗治疗胰腺导管腺癌的患者骨密度受损，而骨密度是远处转移的预测因子。

• DOI: 10.1245/s10434-017-6040-y
• 发表时间: 2017
• 期刊: Ann Surg Oncol.
• 作者: Yamada D;Eguchi H;Iwagami Y;Mukai Y;Hashimoto Y;Asaoka T;Noda T;Kawamoto K;Gotoh K;Kobayashi S;Takeda Y;Tanemura M;Mori M;Doki Y.
• 通讯作者: Doki Y.

Clinical outcome of liver resection in single ceter experience: laparoscopic versus open procedure.

单中心肝切除术的临床结果：腹腔镜手术与开腹手术。

• 发表时间: 2016
• 期刊: E-Book (Advances in Modern Medicine During the Last Decade)
• 作者: Irei T;Tanemura M;Inoue M;Shimizu Y;Tominaga H;Hatanaka N
• 通讯作者: Hatanaka N

Curative Resection for Chemorefractory Advanced Gastric Cancer with Pancreatic Invasion by Pancreatoduodenectomy - A Case Report.

胰十二指肠切除术治愈性切除化疗难治性晚期胃癌伴胰腺侵犯 - 病例报告。

• 发表时间: 2016
• 期刊: Gan To Kagaku Ryoho.
• 作者: Koh M;Kishi K;Tsukada R;Tanemura M;Tei M;Masuzawa T;Suzuki Y;Furukawa K;Ikehara M;Akamatsu H.
• 通讯作者: Akamatsu H.

A practical strategy to pancreatic cancer immunotherapy using resected human lysate vaccines remodeled to express α-gal epitopes

使用经改造表达 α-gal 表位的切除人裂解物疫苗进行胰腺癌免疫治疗的实用策略

• 发表时间: 2018
• 作者: Masahiro Tanemura;Kenta Furukawa;Eiji Miyoshi;Hidetoshi Eguchi;Hiroaki Nagano;Katsuyoshi Matsunami;Satoshi Nagaoka;Kentaro Kishi;Hiroki Akamatsu;Masaki Mori;Yuichiro Doki
• 通讯作者: Yuichiro Doki

Prognostic impact of modified telomerase-specific adenovirus-based identification of viable-peritoneal tumor cells in peritoneal lavage fluid in the patients with potentially resectable pancreatic cancer

基于改良端粒酶特异性腺病毒的腹膜灌洗液中活腹膜肿瘤细胞的鉴定对潜在可切除胰腺癌患者的预后影响

• 发表时间: 2018
• 作者: Masahiro Tanemura;Kenta Furukawa;Manabu Mikamori;Hiroki Akamatsu
• 通讯作者: Hiroki Akamatsu