Mechanisms of association between tumor-promoting inflammation and avoiding immune destruction in renal cell carcinoma

肾细胞癌中促肿瘤炎症与避免免疫破坏之间的关联机制

• 批准号: 16K10997
• 负责人: Saito Kazutaka
• 金额: $ 3万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2020-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K10997/
• 关键词: 腎細胞癌; 炎症; 免疫逃避; 腫瘍免疫; 炎症反応; 免疫療法; 抗腫瘍免疫; 全身性炎症反応; 微小環境; C反応性蛋白; 腫瘍促進性炎症; 免疫抑制

项目成果

Higher Serum C-reactive Protein Level Represents the Immunosuppressive Tumor Microenvironment in Patients With Clear Cell Renal Cell Carcinoma

• DOI: 10.1016/j.clgc.2018.07.027
• 发表时间: 2018-12-01
• 期刊: CLINICAL GENITOURINARY CANCER
• 影响因子: 3.2
• 作者: Nakayama, Takayuki;Saito, Kazutaka;Fujii, Yasuhisa
• 通讯作者: Fujii, Yasuhisa

Higher serum C-reactive protein level represents the immunosuppresive tumor microenvironment in patients with clear cell renal cell carcinoma

较高的血清C反应蛋白水平代表透明细胞肾细胞癌患者的免疫抑制肿瘤微环境

• 发表时间: 2017
• 作者: Nakayama T; Saito K; Inoue M; Ito M;Kijima T;Yoshida S;Yokoyama M; Ishioka J;Matsuoka Y;Kihara K;Fujii Y
• 通讯作者: Fujii Y

Association of Elevated C-Reactive Protein with Oncologic Outcomes in Renal Cell Carcinoma: A Multicenter Analysis.

C 反应蛋白升高与肾细胞癌肿瘤结果的关联：多中心分析。

• 发表时间: 2019
• 作者: Patel S;Meagher M;Saito K;Patil D;Bindayi A;Eldefrawy A;Ryan S;Cotta B;Yim K;Nasseri R;Hamilton Z;Yasuda Y;Fujii Y;Master V;Derweesh I
• 通讯作者: Derweesh I

Elevated C-Reactive Protein is Associated with Functional Decline Following Surgery for Renal Cell Carcinoma: Results of an International Cohort Study.

C 反应蛋白升高与肾细胞癌手术后功能下降相关：一项国际队列研究的结果。

• 发表时间: 2019
• 作者: Cotta B;Saito K;Meagher M;Patil D;Eldefrawy A;Yasuda Y;Bradshaw A;Ryan S;Anyakora D;Yee A;Alksne A;Wan F;Master V;Fujii Y;Derweesh I
• 通讯作者: Derweesh I