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Development of novel supramolecular drug for the treatments of neointimal lesions and aortic aneurysm

Development of novel supramolecular drug for the treatments of neointimal lesions and aortic aneurysm
开发治疗内膜病变和主动脉瘤的新型超分子药物
批准号:
16H05422
负责人:
Miura Yutaka
金额:
$11.32万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2016
资助国家:
日本
项目状态:
已结题
起止时间:
2016-04-01 至 2019-03-31

项目摘要

项目成果

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Targeting ability of self-assembled nanomedicines in rat acute limb ischemia model is affected by size
自组装纳米药物在大鼠急性肢体缺血模型中的靶向能力受尺寸影响
DOI: 10.1016/j.jconrel.2018.07.049
发表时间: 2018
期刊: Journal of Controlled Release
影响因子: 10.8
作者: [Suhara Masamitsu, Miura Yutaka, Cabral Horacio, Akagi Daisuke, Anraku Yasutaka, Kishimura Akihiro, Sano Masaya, Miyazaki Takuya, Nakamura Noriko, Nishiyama Ayako, Kataoka Kazunori, Koyama Hiroyuki, Hoshina Katsuyuki]
通讯作者: Hoshina Katsuyuki
Proteasome inhibitor loaded micelles enhance antitumor activity through macrophage reprogramming by NF-kB inhibition
负载蛋白酶体抑制剂的胶束通过抑制 NF-kB 使巨噬细胞重编程增强抗肿瘤活性
DOI: --
发表时间: 2017
期刊:
影响因子: --
作者: [J. D. Martin, H. Wu, A. Tao, S. Quader, X. Liu, K. Takahashi, L. Hespel, Y. Miura, Y. Hayakawa, T. Irimura, H. Cabral, K. Kataoka]
通讯作者: K. Kataoka
Adequately-sized nanocarriers allow sustained targeted drug delivery to neointimal lesions in rat arteries
足够大小的纳米载体可以将靶向药物持续递送至大鼠动脉的新内膜病变处
DOI: 10.1021/acs.molpharmaceut.6b00219
发表时间: 2016
期刊: Molecular Pharmaceutics
影响因子: 4.9
作者: [R. Taniguchi, Y. Miura, H. Koyama, T. Chida, Y. Anraku, A. Kishimura, K. Shigematsu, K. Kataoka, T. Watanabe]
通讯作者: T. Watanabe
Nanomedicine strategies for enhancing efficacy against head and neck squamous cell carcinoma bearing cancer stem-like cells
增强对抗携带癌症干细胞的头颈鳞状细胞癌疗效的纳米医学策略
DOI: --
发表时间: 2016
期刊:
影响因子: --
作者: [H. Cabral, K. Miyano, M. Wang, Y. Miura, Y. Matsumoto, H. Kinoh, N. Nishiyama, T. Yamasoba, K. Kataoka]
通讯作者: K. Kataoka
28
    Mechanism of sensing blood phosphorus levels and regulation of FGF23 expression
    • 批准号:
      21K16193
    • 项目类别:
      Grant-in-Aid for Early-Career Scientists
    • 资助金额:
      $3.0万
    • 财政年份:
      2021
    • 负责人:
      Miura Yutaka
    • 依托单位:
    Investigation of the pathogenesis of phosphorus metabolism diseases in relation to a novel CPP-dependent Factor X activation mechanism
    • 批准号:
      19K17715
    • 项目类别:
      Grant-in-Aid for Early-Career Scientists
    • 资助金额:
      $2.75万
    • 财政年份:
      2019
    • 负责人:
      Miura Yutaka
    • 依托单位:
    Ligand-incorporated Polymeric Micelles for Advanced Therapeutic Strategies of Arteriosclerosis
    • 批准号:
      24689051
    • 项目类别:
      Grant-in-Aid for Young Scientists (A)
    • 资助金额:
      $15.72万
    • 财政年份:
      2012
    • 负责人:
      Miura Yutaka
    • 依托单位:
    The Environmental Legacy of Winter Olympic Games
    • 批准号:
      24500721
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.41万
    • 财政年份:
      2012
    • 负责人:
      Miura Yutaka
    • 依托单位:
    海外基金