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Development of new therapeutic strategy based on gene expression and mutation profiles in EGFR mutant lung cancer

Development of new therapeutic strategy based on gene expression and mutation profiles in EGFR mutant lung cancer
基于EGFR突变肺癌的基因表达和突变谱开发新的治疗策略
批准号:
16H05431
负责人:
Toyooka Shinichi
金额:
$11.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2016
资助国家:
日本
项目状态:
已结题
起止时间:
2016-04-01 至 2019-03-31

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Multiple acquired resistance mechanisms against third generation EGFR-TKI osimertinib in non-small cell lung cancer cells
非小细胞肺癌细胞对第三代EGFR-TKI奥希替尼的多重获得性耐药机制
DOI: --
发表时间: 2017
期刊:
影响因子: --
作者: [Kei Namba, Kazuhiko Shien, Hidejiro Torigoe, Hiroki Sato, Hiromasa Yamamoto, Junichi Soh, Kazunori Tsukuda, Shinichi Toyooka]
通讯作者: Shinichi Toyooka
DOI: 10.1186/s12885-019-5374-1
发表时间: 2019-02-26
期刊: BMC CANCER
影响因子: 3.8
作者: [Namba, Kei, Tomida, Shuta, Toyooka, Shinichi]
通讯作者: Toyooka, Shinichi
DOI: 10.1158/1541-7786.mcr-18-0628
发表时间: 2019-02-01
期刊: MOLECULAR CANCER RESEARCH
影响因子: 5.2
作者: [Namba, Kei, Shien, Kazuhiko, Toyooka, Shinichi]
通讯作者: Toyooka, Shinichi
Detection of multiple low-frequency mutations by molecular-barcode sequencing
通过分子条形码测序检测多个低频突变
DOI: --
发表时间: 2017
期刊:
影响因子: --
作者: [Kei Namba, Shuta Tomida, Hidejiro Torigoe, Hiroki Sato, Kazuhiko Shien, Hiromasa Yamamoto, Junichi Soh, Kazunori Tsukuda, Shinichi Toyooka]
通讯作者: Shinichi Toyooka
Development of the novel therapy focused on damage-associated molecular patterns (DAMPs) for lung fibrosis-related diseases
  • 批准号:
    19H03746
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.15万
  • 财政年份:
    2019
  • 负责人:
    Toyooka Shinichi
  • 依托单位:
Development of innovative therapeutic antibodies targeting the inflammatory tumor microenvironment in refractory thoracic tumors
  • 批准号:
    18K19581
  • 项目类别:
    Grant-in-Aid for Challenging Research (Exploratory)
  • 资助金额:
    $3.99万
  • 财政年份:
    2018
  • 负责人:
    Toyooka Shinichi
  • 依托单位:
New therapeutic strategy for non-small cell lung cancer by REIC gene therapy
  • 批准号:
    26670627
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.33万
  • 财政年份:
    2014
  • 负责人:
    Toyooka Shinichi
  • 依托单位:
Understanding and overcoming drug resistance to EGFR-inhibitors for lung cancer
  • 批准号:
    25293302
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $10.82万
  • 财政年份:
    2013
  • 负责人:
    Toyooka Shinichi
  • 依托单位:
海外基金