Elucidation of the mechanism of Sortilin reduction by prion infection and its application to therapeutic method development
Elucidation of the mechanism of Sortilin reduction by prion infection and its application to therapeutic method development
批准号:
17K08859
负责人:
UCHIYAMA Keiji
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2017
资助国家:
日本
项目状态:
已结题
起止时间:
2017-04-01 至 2020-03-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Identification and investigation of a novel anti-prion compound.
新型抗朊病毒化合物的鉴定和研究。
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Uchiyama, K and Sakaguchi S.]
通讯作者:
K and Sakaguchi S.
DOI:
10.1371/journal.ppat.1006470
发表时间:
2017-06
期刊:
PLoS pathogens
影响因子:
6.7
作者:
[Uchiyama K, Tomita M, Yano M, Chida J, Hara H, Das NR, Nykjaer A, Sakaguchi S]
通讯作者:
Sakaguchi S
Prion Protein Devoid of the Octapeptide Repeat Region Delays BSE Pathogenesis in Mice.
缺乏八肽重复区域的朊病毒蛋白可延迟小鼠 BSE 发病机制。
DOI:
--
发表时间:
2017
期刊:
Journal of Virology
影响因子:
5.4
作者:
[2.Hara H, Miyata H, Das N, Chida J, Yoshimochi T, Uchiyama K, Watanabe H, Kondoh G, Yokoyama T and Sakaguchi S.]
通讯作者:
Yokoyama T and Sakaguchi S.
Prion propagation through sortilin degradation.
朊病毒通过分拣蛋白降解进行传播。
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Tomohiko Sadaoka, Daniel P. Depledge, Labchan Rajbhandari, Arun Venkatesan, Jeffrey I. Cohen, Judith Breuer, Yasuko Mori, Sakaguchi S and Uchiyama K]
通讯作者:
Sakaguchi S and Uchiyama K
Intracellular secretion analysis of recombinant therapeutic antibodies in engineered CHO cells aiming to establish high produce.
工程化 CHO 细胞中重组治疗性抗体的细胞内分泌分析,旨在建立高产量。
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Kaneyoshi K, Uchiyama K, Onitsuka M, Yamano N, Koga Y and Omasa T]
通讯作者:
Koga Y and Omasa T
共 6 条
Development of basic technology for therapy of prion diseases based on Sortilin function
-
批准号:26460557
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.24万
-
财政年份:2014
-
负责人:UCHIYAMA Keiji
-
依托单位:
Role of BIG2, a Guanine-Nucleotide Exchanging factor for ADP-Ribosylation Factors, in Insulin-Regulated Glucose Transporter Translocation
-
批准号:21570142
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.08万
-
财政年份:2009
-
负责人:UCHIYAMA Keiji
-
依托单位:
海外基金