Phylogenomics of Spiralia: Syndermata, Gnathifera and the Platyzoa hypothesis

螺旋菌的系统发育组学：Syndermata、Gnathifera 和 Platyzoa 假说

• 批准号: 5452203
• 负责人: Professor Dr. Thomas Hankeln
• 金额: --
• 依托单位: Arbeitsgruppe Hankeln - Molekulargenetik und Genomanalyse
• 依托单位国家: 德国
• 项目类别: Priority Programmes
• 财政年份: 2005
• 资助国家: 德国
• 起止时间: 2004-12-31 至 2013-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/5452203?language=en
• 关键词: Phylogenomics; Spiralia; Syndermata; Gnathifera; Platyzoa

Nemathelminthes and Gnathifera, historically joined as Aschelminthes, comprise fundamentally diverse worm-like organisms, which have been grouped into a number of distinct animal phyla. The phylogenetic affiliations of these phyla are controversial, being involved in the `Coelomata` and `Ecdysozoa` debates. The worm-like Xenoturbella is another enigmatic taxon, which may represent a novel deuterostome lineage. Within the framework of the priority project Deep Metazoan Phylogeny , we propose to initially gene rate 4000 EST reads each for one nematomorph species, one acanthocephalan and for Xenoturbella. These data will be used to reconstruct `deep` branches of the metazoan tree and to select genes, which can be employed to resolve controversial relationships within the phyla. - In a bioinformatical analysis of the EST data, the basic features of the gene coding regions and the gene repertoire of the three taxa will be studied in comparison with other genomic model organisms. This promises to improve our view of the basic metazoan gene content and the evolutionary transition from invertebrate to vertebrate genomes. Additionally, we will focus on the evolution of invertebrate globin genes with regard to recently discovered, novel vertebrate globins.

线虫和颚类，历史上被称为无肠线虫，包括基本上不同的蠕虫状生物，它们被分为许多不同的动物门。这些门的系统发生关系是有争议的，涉及到`体腔动物'和`蜕皮动物'的辩论。蠕虫状的Xenoturbella是另一个神秘的分类群，可能代表了一个新的后口动物谱系。在优先项目深后生动物系统发育的框架内，我们建议最初的基因率4000 EST读取每个线虫物种，一个棘头虫和Xenoturbella。这些数据将用于重建后生动物树的“深层”分支，并选择基因，这些基因可用于解决门内有争议的关系。- 在EST数据的生物信息学分析中，将与其他基因组模式生物进行比较，研究这三个分类群的基因编码区和基因库的基本特征。这有望改善我们的基本后生动物基因的内容和从无脊椎动物到脊椎动物基因组的进化过渡的看法。此外，我们将集中在进化的无脊椎动物珠蛋白基因方面最近发现的，新的脊椎动物珠蛋白。