FOR 521: Regulation of Immunological Processes by Membrane Proximal Signaling Modules

该研究单位旨在阐明免疫细胞内受体介导的激活和分化事件的分子机制。研究小组将研究免疫细胞功能的三个主要方面。四个项目评估免疫受体介导的信号转导的分子基础。本文将应用生物化学、分子生物学和细胞生物学的现代技术，研究新的跨膜和细胞质转换蛋白的功能。已经建立了几个淘汰模型，这些模型将促进这一重点的研究。

The Research Unit aims at elucidating the molecular mechanisms underlying receptor-mediated activation and differentiation events within immunocompetent cells. Within the research group three major aspects of immune cell functions will be investigated. Four projects assess the molecular basis of immunoreceptor-mediated signal transduction. Here the functions of new transmembrane and cytosolic adapter proteins will be investigated by applying modern techniques in biochemistry, molecular biology and cell biology. Several knock-out models have been established which will facilitate the research within this focus.