SFB 416: Chemische und biologische Synthese und Transformation von Naturstoffen und Naturstoff-Analoga

SFB 416：天然产物和天然产物类似物的化学和生物合成及转化

• 批准号: 5480236
• 金额: --
• 依托单位: Georg-August-Universität Göttingen
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 1996
• 资助国家: 德国
• 起止时间: 1995-12-31 至 2005-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/5480236?language=en
• 关键词: SFB; 416; Chemische; und; biologische

The aim of the collaborative research centre 416 is the chemical and biological synthesis and transformation of important bioactive natural products and their analogues. For this purpose, highly efficient and selective synthetic methods will be developed and employed. A point of emphasis is the use of catalytic procedures. In addition, the enzymatic potential of Nature - either directly or after gene technical variation - will be exploited. An integral part of the project is the investigation of the biological activity of the prepared compounds and a clarification of their mode of action. The collaborative research centre 416 shall provide a better access to some important and interesting natural products and their analogues by developing new chemical and biochemical methods on the one hand, and on the other hand contribute to a deeper understanding of important interactions of biological systems.

合作研究中心416的目标是化学和生物合成和重要的生物活性天然产品及其类似物的转化。为此，将开发和采用高效和选择性的合成方法。一个重点是使用催化程序。此外，自然界的酶潜力-直接或基因技术变异后-将被利用。该项目的一个组成部分是调查所制备化合物的生物活性并澄清其作用方式。合作研究中心416将通过开发新的化学和生物化学方法，一方面提供更好地获得一些重要和有趣的天然产物及其类似物的途径，另一方面有助于更深入地了解生物系统的重要相互作用。