identifying and strenghtening the neural circuits of positive motivation

识别和加强积极动机的神经回路

• 批准号: 22K11601
• 负责人: グレニエ フランソワ
• 金额: $ 2.41万
• 依托单位: University of Tsukuba
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2022
• 资助国家: 日本
• 起止时间: 2022-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K11601/
• 关键词: Motivation; Exercise; Electrophysiology; Treadmill; Running; Brain oscillations; Hippocampus; Health; mild running; motivation; electrophysiology; EEG; local field potential

We are studying the brain networks involved in the positive motivational impact of light-exercise running (LER) in rats. We have established a method to perform electrical activity recordings of different brain regions before, during and after (LER) on a treadmill. The positive activating impact of LER was revealed by a general increase in wake and a specific increase in hippocampal theta waves (HTW) during and after exercise. These HTW are involved in alertness, locomotion and cognitive processes. Our preliminary results also showed that transfer to the treadmill is itself an activating event. We therefore used these early results to modify our protocol to enhance the contrast between running and sedentary group by increasing the period of rest before LER.

我们正在研究参与轻度运动跑步（LER）对大鼠的积极激励影响的大脑网络。我们已经建立了一种方法来执行不同的大脑区域的电活动记录之前，期间和之后（LER）在跑步机上。运动期间和运动后，觉醒的普遍增加和海马θ波（HTW）的特定增加揭示了LER的积极激活影响。这些HTW涉及警觉、运动和认知过程。我们的初步结果也表明，转移到跑步机本身就是一个激活事件。因此，我们使用这些早期结果来修改我们的方案，通过增加LER前的休息时间来增强跑步组和久坐组之间的对比。