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identifying and strenghtening the neural circuits of positive motivation

identifying and strenghtening the neural circuits of positive motivation
识别和加强积极动机的神经回路
批准号:
22K11601
负责人:
グレニエ フランソワ
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2022
资助国家:
日本
项目状态:
已结题
起止时间:
2022-04-01 至 2024-03-31

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中文摘要
翻译
我们正在研究与轻度运动跑步(LER)对大鼠的积极激励作用有关的大脑网络。我们已经建立了一种方法,在跑步机上进行运动前、中、后不同脑区的电活动记录。LER的积极激活作用表现为运动中和运动后觉醒的普遍增加和海马theta波(HTW)的特异性增加。这些HTW与警觉性、运动性和认知过程有关。我们的初步结果还表明,转移到跑步机上本身就是一种激活事件。因此,我们使用这些早期的结果来修改我们的方案,通过增加LER前的休息时间来增强跑步组和久坐组之间的对比。
英文摘要
We are studying the brain networks involved in the positive motivational impact of light-exercise running (LER) in rats. We have established a method to perform electrical activity recordings of different brain regions before, during and after (LER) on a treadmill. The positive activating impact of LER was revealed by a general increase in wake and a specific increase in hippocampal theta waves (HTW) during and after exercise. These HTW are involved in alertness, locomotion and cognitive processes. Our preliminary results also showed that transfer to the treadmill is itself an activating event. We therefore used these early results to modify our protocol to enhance the contrast between running and sedentary group by increasing the period of rest before LER.
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