Chemotaxonomic studies of the red algal genus Laurencia

劳伦西亚红藻属的化学分类学研究

• 批准号: 09839001
• 负责人: MASUDA Michio
• 金额: $ 2.11万
• 依托单位: HOKKAIDO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09839001/
• 关键词: Chemotaxonomy; Halogenated secondary metabolites; Marine algae; Rhodophyta; Rhodomelaceae; Laurencia; terpenoid; acetogenin; 含ハロゲン化合物; 抗菌作用; chemical race

(1) A new species, Laurencia omaezakiana Masuda that is distributed in the warm temperate region of the Pacific coast of Japan was established on the basis of morphological and chemical features. It produces a characteristic triterpenoid, enshuol.(2) Laurencia japonensis Masuda et Abe widely distributed along the coasts of Japan except for Hokkaido and Okinawa was described as a new species on the basis of morphological and chemical features as well as the presence of complete reproductive isolation between related species. Three novel secondary metabolites were reported from this species : anhydroaplysiadiol (diterpenoid) and japonenyne-A and japonenyne-B (C_<15> acetogenin).(3) Genetic variation in the synthesis of halogenated secondary metabolites and affinity between chemical races in Laurencia nipponica Yamada were investigated in laboratory crossing experiments and chemical analyses.(4) Three sesquiterpenoids were detected from Laurencia majuscula (Harvey) Lucas growing in Okinaw … More a and Kagoshima for the first time, which indicates that this worldwide distributed species includes 4 chemical races. The occurrence of a novel sesquiterpenoid, 10-bromo-9-hydroxy-chamigra-2,7(14)-diene in the Nago population in Okinawa indicates that diversification in the synthesis of halogenated secondary metabolites still continues within a single race that is distributed in the western Pacific ranging from Queensland (Australia) to Okinoshima, Kochi (Japan).(5) An unidentified species of Laurencia that was collected from Okinawa and is considered to be a new species produces two novel C_<15> acetogenins, bisezakyne-A and bisezakyne-B.(6) A novel C_<15>, acetogenin, mariannenyne, was isolated from Laurencia mariannensis Yamada which was collected from Okinawa.(7) Two novel C_<15> acetogenins, lembyne-A and lembyne-B, were isolated from an unidentified species of Laurencia that was collected from Kedah, Malaysia, and two novel sesquiterpenoids, pannosane and pannosanol, were isolated from Laurencia pannosa Zanardini that was collected from an island close to its type locality, Tanjung Datu, Sarawak (Malaysia). Less

(1)根据形态和化学特征，建立了分布于日本太平洋沿岸暖温带的一新种--Laurencia omaezakiana Masuda。它能产生一种特有的三萜类化合物--恩舒醇。(2)日本劳伦西亚除北海道和冲绳外，广泛分布于日本沿海，根据其形态和化学特征以及近缘种之间存在的完全生殖隔离，被描述为一新种。从该物种中分离得到3种新的次生代谢物：脱水二醇(二萜类)和菊烯-A和菊烯-B(C_&lt；15&gt；乙酸根素)。(3)通过实验室杂交实验和化学分析，研究了日本劳伦西亚Yamada卤代次生代谢物合成的遗传变异和化学小种间的亲和力。(4)从生长在Okinaw…上的大月桂中检测到三种倍半萜类化合物。More a和鹿儿岛(Kagoshima)，这表明这一全球分布的物种包括4个化学小种。一种新的倍半萜类化合物10-溴-9-羟基-2，7(14)-二烯在冲绳名护市种群中的出现表明，卤化次生代谢物的合成仍然在从澳大利亚昆士兰到日本冲绳岛的西太平洋地区的一个单一小种内继续多样化。(5)采自冲绳的一种未鉴定的劳伦西亚被认为是一新种，产生两个新的C&lt；15&gt；乙酸原素类，Bisezakyne-A和Bisezakyne-B。(7)从采自马来西亚基达的一个未鉴定种中分离得到两个新的C&lt；15&gt；Cembyne-A和Lembyne-B，从马来西亚沙捞越的丹绒岛上分离到两个新的倍半萜类化合物Pannosane和Pannosanol。较少

项目成果

Suzuki,M.: "Bisezakyne-A and -B, halogenated C_<15> acetogenins from a Japanese Laurencia species "Phytochemistry. 51. 657-662 (1999)

Suzuki,M.：“Bisezakyne-A 和 -B，来自日本劳伦西亚物种的卤化 C_15 乙酰基”植物化学。

Suzuki, M.: "Bisezakyne-A and -B, halogenated C_<15> acetogenins from a Japanese Laurencia species"Phytochemistry. 51-4. 657-662 (1999)

Suzuki，M.：“Bisezakyne-A和-B，来自日本Laurencia物种的卤化C_ 15 acetogenins”植物化学。

Abe, T.: "Chemical races in the red alga Laurencia nipponica (Rhodomelaceae, Ceramiales)"Phycological Research. 47-2. 87-95 (1999)

Abe, T.：“红藻 Laurencia nipponica（Rhodomelaceae，Ceramiales）中的化学种族”藻类研究。

Suzuki,M.: "Scanlonenyne,a novel halogenated C_<15> acetogenin from the red alga Laurencia obtusa in Irish waters" Tetrahedron. 53・12. 4271-4278 (1997)

Suzuki, M.：“Scanlonenyne，一种来自爱尔兰水域红藻 Laurencia obtusa 的新型卤化 C_<15> acetogenin”，Tetrahedron 53・12 (1997)。

Abe,T.: "Laurencia japonensis sp.nov.(Ceramiales, Rhodophyta)"European Journal of Phycology. 33. 17-24 (1998)

Abe,T.：“Laurencia japonensis sp.nov.（Ceramiales，Rhodophyta）”欧洲藻类学杂志。