Identification of the novel therapeutic target molecules for leukemia stem cells based on TIM-3/galectin-9 interaction
Identification of the novel therapeutic target molecules for leukemia stem cells based on TIM-3/galectin-9 interaction
批准号:
26713034
负责人:
Kikushige Yoshikane
金额:
$9.48万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (A)
财政年份:
2014
资助国家:
日本
项目状态:
已结题
起止时间:
2014-04-01 至 2016-03-31
中文摘要
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白血病幹細胞におけるTIM-3/galectin-9 オートクラインシグナル機構の解明
白血病干细胞TIM-3/galectin-9自分泌信号传导机制的阐明
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[R. Kobayashi, A. Kato, S. Oda, N. Koyanagi, M. Oyama, H. Kozuka-Hata, J. Arii, and Y. Kawaguchi., 古澤 之裕, 菊繁吉謙]
通讯作者:
菊繁吉謙
Identification of TIM-3 as a functional leukemic stem cell surface molecule in primary human myeloid leukemia
鉴定 TIM-3 作为原发性人髓性白血病功能性白血病干细胞表面分子
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[S. Oda, J. Arii, N. Koyanagi, A. Kato, and Y. Kawaguchi., 菊繁吉謙]
通讯作者:
菊繁吉謙
TIM-3, a leukemia stem cell marker, plays a role in leukemic transformation through autocrine stimulatory signaling by its ligand, galectin-9
TIM-3 是一种白血病干细胞标记物,通过其配体 galectin-9 的自分泌刺激信号在白血病转化中发挥作用
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Shindo K, Kato A, Koyanagi N, Sagara H, Arii J, Kawaguchi Y., 菊繁吉謙]
通讯作者:
菊繁吉謙
白血病幹細胞抗原TIM-3の機能解明、および新規標的治療の開発
白血病干细胞抗原TIM-3功能的阐明及新型靶向治疗的开发
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Arii J, Shindo K, Koyanagi N, Kato A, Kawaguchi Y., 菊繁吉謙]
通讯作者:
菊繁吉謙
TIM-3 and its ligand, galectin-9 constitute a pan-myeloid autocrine loop to develop and maintain malignant stem cells in most human myeloid leukemia
TIM-3及其配体半乳糖凝集素9构成泛骨髓自分泌环,在大多数人髓性白血病中发育和维持恶性干细胞
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Y. Hirohata, A. Kato, M. Oyama, H. Kozuka-Hata, N. Koyanagi, J. Arii and Y. Kawaguchi., 古澤 之裕, 菊繁吉謙]
通讯作者:
菊繁吉謙
共 6 条
Establishment of novel therapeutic strategies against cancers via identification of neosubstrate of IMiDs
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批准号:20K21617
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.16万
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财政年份:2020
-
负责人:Kikushige Yoshikane
-
依托单位:
Identification of human acute leukemia specific metabolic pathways
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批准号:19H03687
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.15万
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财政年份:2019
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负责人:Kikushige Yoshikane
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依托单位:
Elucidation of the function of exhaustion-related molecules in human leukemic stem cells
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批准号:16H06250
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项目类别:Grant-in-Aid for Young Scientists (A)
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资助金额:$15.39万
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财政年份:2016
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负责人:Kikushige Yoshikane
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依托单位:
海外基金