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Study on international standard of cold provocation test for evaluating peripheral circulatory functionr in hand-transmitted vibration diseases

手传振动病末梢循环功能冷激发试验国际标准研究

基本信息

批准号：
09670425
负责人：
ISHITAKE Tatsuya
金额：
$ 0.7万
依托单位：
KURUME UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1997
资助国家：
日本
起止时间：
1997 至 2000
项目状态：
已结题

项目摘要

ISO has started to establish an international standard for a cold provocation test as a peripheral circulatory function since 1996. The aim of this study is to clarify the effects of test room temperature on skin temperature, vibrotactile and heat pain threshold under strictly controlled room temperature, and propose a new significance of the cold provocation test. Significant differences of skin temperature among three room conditions were observed before and 3 min after cold provocation. The skin temperature at the end of measurement at 27℃ of room temperature returned to the previous level in the most of the subjects. On the other hand, 40% and 15% of the subjects only recovered within 15 min after provocation in case of 22℃ and 17℃, respectively. The changes of the mean heat pain and vibrotactile threshold were strongly influenced by room temperatures. There was a significant negative relationship between skin temperature and both thresholds except the value of previous vibrotactile threshold. The recovery of vibrotactile threshold was more faster than that of heat pain threshold. The response of skin temperature, vibrotactile and heat pain thresholds in the 3 provocation test were strongly related to the room temperature. According to the types of provocation test, an adaptable temperature of the test room should be considered. The simultaneous measurement of heat pain threshold and skin temperature can provide some useful information for evaluating the periphearl nervous system.

ISO从1996年开始建立冷激发试验作为外周循环功能的国际标准。本研究旨在阐明严格控制室温条件下，实验室温度对皮温、振动触觉和热痛阈的影响，并提出冷激发实验的新意义。在冷刺激前和冷刺激后3min，三种室内条件下的皮肤温度差异显著。在室温27℃下测量结束时，大多数受试者的皮温恢复到以前的水平。另一方面，在22℃和17℃的情况下，分别有40%和15%的受试者仅在激发后15分钟内恢复。平均热痛和振动触觉阈值的变化受室温的强烈影响。除先前的振动触觉阈值外，皮肤温度与两个阈值均呈显著负相关。振动觉阈的恢复比热痛阈的恢复快。3种激发试验中皮温、振动触觉和热痛阈的反应与室温密切相关。根据激发试验的类型，应考虑适宜的试验室温度。同时测定热痛阈和皮肤温度可为周围神经系统的评价提供有用的信息。